Rapamycin-Insensitive Companion of mTOR Protein
"Rapamycin-Insensitive Companion of mTOR Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adaptor protein subunit of MTORC2 COMPLEX. It functions as a structural component and is phosphorylated by RIBOSOMAL PROTEIN S6 KINASES, integrating signals for cell growth and proliferation, especially during embryonic development.
Descriptor ID |
D000076226
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MeSH Number(s) |
D05.500.356.500 D08.811.913.696.620.682.700.931.750.500 D12.644.360.024.323 D12.776.157.057.156 D12.776.476.024.411 D12.776.476.925.750.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rapamycin-Insensitive Companion of mTOR Protein".
Below are MeSH descriptors whose meaning is more specific than "Rapamycin-Insensitive Companion of mTOR Protein".
This graph shows the total number of publications written about "Rapamycin-Insensitive Companion of mTOR Protein" by people in this website by year, and whether "Rapamycin-Insensitive Companion of mTOR Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 0 | 1 | 1 |
2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Rapamycin-Insensitive Companion of mTOR Protein" by people in Profiles.
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Inhibition of RhoA and mTORC2/Rictor by Fingolimod (FTY720) induces p21-activated kinase 1, PAK-1 and amplifies podosomes in mouse peritoneal macrophages. Immunobiology. 2018 11; 223(11):634-647.
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RICTOR gene amplification is correlated with metastasis and therapeutic resistance in triple-negative breast cancer. Pharmacogenomics. 2018 06 01; 19(9):757-760.
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Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis. Breast Cancer Res. 2017 Jun 30; 19(1):74.