"Calmodulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The binding of calcium ions to this protein allows this protein to bind to cyclic nucleotide phosphodiesterases and to adenyl cyclase with subsequent activation. Thereby this protein modulates cyclic AMP and cyclic GMP levels.
| Descriptor ID |
D002147
|
| MeSH Number(s) |
D12.644.360.372.249 D12.776.157.125.412.249 D12.776.476.387.249
|
| Concept/Terms |
Calmodulin- Calmodulin
- Calcium-Dependent Regulator
- Calcium Dependent Regulator
- Calcium-Dependent Activator Protein
- Activator Protein, Calcium-Dependent
- Calcium Dependent Activator Protein
- Protein, Calcium-Dependent Activator
- Phosphodiesterase Protein Activator
- Activator, Phosphodiesterase Protein
- Protein Activator, Phosphodiesterase
- Phosphodiesterase Activating Factor
- Activating Factor, Phosphodiesterase
- Factor, Phosphodiesterase Activating
- Phosphodiesterase Activator Protein
- Activator Protein, Phosphodiesterase
- Protein, Phosphodiesterase Activator
- Regulator, Calcium-Dependent
- Regulator, Calcium Dependent
Cyclic AMP-Phosphodiesterase Activator- Cyclic AMP-Phosphodiesterase Activator
- AMP-Phosphodiesterase Activator, Cyclic
- Activator, Cyclic AMP-Phosphodiesterase
- Cyclic AMP Phosphodiesterase Activator
|
Below are MeSH descriptors whose meaning is more general than "Calmodulin".
Below are MeSH descriptors whose meaning is more specific than "Calmodulin".
This graph shows the total number of publications written about "Calmodulin" by people in this website by year, and whether "Calmodulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2017 | 1 | 3 | 4 |
| 2018 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Calmodulin" by people in Profiles.
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Calmodulin mutations and life-threatening cardiac arrhythmias: insights from the International Calmodulinopathy Registry. Eur Heart J. 2019 09 14; 40(35):2964-2975.
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Epidemiology of Aspergillus species causing keratitis in Mexico. Mycoses. 2019 Feb; 62(2):144-151.
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Loss of S100A1 expression leads to Ca2+ release potentiation in mutant mice with disrupted CaM and S100A1 binding to CaMBD2 of RyR1. Physiol Rep. 2018 08; 6(15):e13822.
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Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis. Nat Microbiol. 2018 07; 3(7):791-803.
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A framework for exhaustively mapping functional missense variants. Mol Syst Biol. 2017 12 21; 13(12):957.
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Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity. Elife. 2017 10 02; 6.
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Genetic Diversity and In Vitro Antifungal Susceptibility of 200 Clinical and Environmental Aspergillus flavus Isolates. Antimicrob Agents Chemother. 2017 05; 61(5).
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Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes. Cardiovasc Res. 2017 Apr 01; 113(5):531-541.
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Functional analysis of the stress-inducible soybean calmodulin isoform-4 (GmCaM-4) promoter in transgenic tobacco plants. Mol Cells. 2009 Apr 30; 27(4):475-80.
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The identification of a calmodulin-binding domain within the cytoplasmic tail of angiotensin-converting enzyme-2. Endocrinology. 2009 May; 150(5):2376-81.