"Cocaine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
| Descriptor ID |
D003042
|
| MeSH Number(s) |
D02.145.074.722.388 D03.132.889.354 D03.605.084.500.722.388 D03.605.869.388
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cocaine".
Below are MeSH descriptors whose meaning is more specific than "Cocaine".
This graph shows the total number of publications written about "Cocaine" by people in this website by year, and whether "Cocaine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 6 | 1 | 7 |
| 2018 | 11 | 4 | 15 |
| 2019 | 4 | 0 | 4 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cocaine" by people in Profiles.
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HIV Risk Among Urban and Suburban People Who Inject Drugs: Elevated Risk Among Fentanyl and Cocaine Injectors in Maryland. AIDS Behav. 2022 Jan; 26(1):277-283.
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The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis. Curr Opin Psychiatry. 2021 07 01; 34(4):344-350.
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Levamisole-a Toxic Adulterant in Illicit Drug Preparations: a Review. Ther Drug Monit. 2021 04 01; 43(2):221-228.
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Shifts in drug seizures in the United States during the COVID-19 pandemic. Drug Alcohol Depend. 2021 04 01; 221:108580.
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Increased HIV testing in people who use drugs hospitalized in the first wave of the COVID-19 pandemic. J Subst Abuse Treat. 2021 05; 124:108266.
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COVID-19 Pandemics: A Surprising Link to Bread Flour With Collateral Damage to a Prosthetic Heart Valve. Circ Cardiovasc Imaging. 2020 10; 13(10):e011395.
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Levamisole-adulterated cocaine poses a concern during the COVID-19 pandemic. J Addict Dis. 2020 Oct-Dec; 38(4):580-581.
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In vivo characterization of toxicity of norcocaethylene and norcocaine identified as the most toxic cocaine metabolites in male mice. Drug Alcohol Depend. 2019 11 01; 204:107462.
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Authors' reply to comment on "Epidemiology, clinical features and management of patients presenting to European emergency departments with acute cocaine toxicity: comparison between powder cocaine and crack cocaine cases". Clin Toxicol (Phila). 2020 01; 58(1):72-74.
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Enhanced toxicity from powder cocaine use in comparison to crack cocaine use - an observational study in the intensive care unit. Clin Toxicol (Phila). 2020 01; 58(1):71-72.