"Microbial Collagenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
Descriptor ID |
D003012
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MeSH Number(s) |
D08.811.277.656.300.480.205.500 D08.811.277.656.675.374.205.500
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Concept/Terms |
Microbial Collagenase- Microbial Collagenase
- Clostridium histolyticum Collagenase
- Collagenase, Clostridium histolyticum
- Nucleolysin
- Collagenase, Microbial
- Collalysine
- Clostridiopeptidase A
- Collagenase Clostridium histolyticum
- Clostridium histolyticum, Collagenase
- histolyticum, Collagenase Clostridium
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Below are MeSH descriptors whose meaning is more general than "Microbial Collagenase".
Below are MeSH descriptors whose meaning is more specific than "Microbial Collagenase".
This graph shows the total number of publications written about "Microbial Collagenase" by people in this website by year, and whether "Microbial Collagenase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 0 | 1 |
2018 | 4 | 0 | 4 |
2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Microbial Collagenase" by people in Profiles.
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Editorial Comment. J Urol. 2019 04; 201(4):782.
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Allergic contact dermatitis caused by chloramphenicol with prurigo nodularis-like spreading. Contact Dermatitis. 2019 Apr; 80(4):251-252.
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Sildenafil 25 mg ODT + Collagenase Clostridium hystoliticum vs Collagenase Clostridium hystoliticum Alone for the Management of Peyronie's Disease: A Matched-Pair Comparison Analysis. J Sex Med. 2018 10; 15(10):1472-1477.
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Predictors of treatment success after collagenase Clostridium histolyticum injection for Peyronie's disease: development of a nomogram from a multicentre single-arm, non-placebo controlled clinical study. BJU Int. 2018 10; 122(4):680-687.
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Collagenase clostridium histolyticum for the treatment of Peyronie's disease: a prospective Italian multicentric study. Andrology. 2018 07; 6(4):564-567.
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Predictive Factors of Patients' and Their Partners' Sexual Function Improvement After Collagenase Clostridium Histolyticum Injection for Peyronie's Disease: Results From a Multi-Center Single-Arm Study. J Sex Med. 2018 05; 15(5):716-721.
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Safety and effectiveness of collagenase clostridium histolyticum in the treatment of Peyronie's disease using a new modified shortened protocol. BJU Int. 2017 11; 120(5):717-723.
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Lysyl oxidase and collagenase in experimental acute and chronic liver injury. Gastroenterology. 1982 Mar; 82(3):526-34.