Heat Shock Transcription Factors
"Heat Shock Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3' pentamer DNA sequences and are regulated by poly(ADP) ribosylation. They play essential roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress.
| Descriptor ID |
D000076249
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| MeSH Number(s) |
D12.776.157.687.450 D12.776.260.260 D12.776.660.720.462 D12.776.930.317
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Heat Shock Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Heat Shock Transcription Factors".
This graph shows the total number of publications written about "Heat Shock Transcription Factors" by people in this website by year, and whether "Heat Shock Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 2 | 3 |
| 2018 | 6 | 1 | 7 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heat Shock Transcription Factors" by people in Profiles.
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Light Primes the Thermally Induced Detoxification of Reactive Oxygen Species During Development of Thermotolerance in Arabidopsis. Plant Cell Physiol. 2019 Jan 01; 60(1):230-241.
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PR-957, a selective immunoproteasome inhibitor, reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1. Biochem Pharmacol. 2018 10; 156:511-523.
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The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer. Nucleic Acids Res. 2018 06 20; 46(11):5587-5600.
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TG2 regulates the heat-shock response by the post-translational modification of HSF1. EMBO Rep. 2018 07; 19(7).
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HSF1 deficiency accelerates the transition from pressure overload-induced cardiac hypertrophy to heart failure through endothelial miR-195a-3p-mediated impairment of cardiac angiogenesis. J Mol Cell Cardiol. 2018 05; 118:193-207.
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Heat shock protein (Hsp) regulation by muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus. J Cell Physiol. 2018 08; 233(8):6107-6116.
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Heat shock factor 1 suppresses the HIV-induced inflammatory response by inhibiting nuclear factor-?B. Cell Immunol. 2018 05; 327:26-35.
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Regulation of HSF1 protein stabilization: An updated review. Eur J Pharmacol. 2018 Mar 05; 822:69-77.
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HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants. J Pineal Res. 2017 Mar; 62(2).
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Methylene blue increases the amount of HSF1 through promotion of PKA-mediated increase in HSF1-p300 interaction. Int J Biochem Cell Biol. 2017 03; 84:75-88.