Arachidonate 15-Lipoxygenase
"Arachidonate 15-Lipoxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.
| Descriptor ID |
D001093
|
| MeSH Number(s) |
D08.811.682.690.416.583.500.065 D12.776.556.579.374.568.500.030
|
| Concept/Terms |
Arachidonate 15-Lipoxygenase- Arachidonate 15-Lipoxygenase
- 15-Lipoxygenase, Arachidonate
- Arachidonate 15 Lipoxygenase
- Arachidonic Acid 15-Lipoxygenase
- 15-Lipoxygenase, Arachidonic Acid
- Arachidonic Acid 15 Lipoxygenase
- 15-Lipoxygenase
- 15 Lipoxygenase
|
Below are MeSH descriptors whose meaning is more general than "Arachidonate 15-Lipoxygenase".
Below are MeSH descriptors whose meaning is more specific than "Arachidonate 15-Lipoxygenase".
This graph shows the total number of publications written about "Arachidonate 15-Lipoxygenase" by people in this website by year, and whether "Arachidonate 15-Lipoxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Arachidonate 15-Lipoxygenase" by people in Profiles.
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Deciphering the Molecular Details of the Lipoxin Formation Mechanism in the 5(S),15(S)-DiHpETE Biosynthetic Pathway Catalyzed by Reticulocyte 15-Lipoxygenase-1. J Phys Chem B. 2020 12 17; 124(50):11406-11418.
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Elevated AA/EPA Ratio Represents an Inflammatory Biomarker in Tumor Tissue of Metastatic Colorectal Cancer Patients. Int J Mol Sci. 2019 Apr 25; 20(8).
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Transcriptomic and lipidomic profiling of eicosanoid/docosanoid signalling in affected and non-affected skin of human atopic dermatitis patients. Exp Dermatol. 2019 02; 28(2):177-189.
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Inhibition of Arachidonate 12/15-Lipoxygenase Improves a-Galactosidase Efficacy in iPSC-Derived Cardiomyocytes from Fabry Patients. Int J Mol Sci. 2018 May 16; 19(5).
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A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarin. Chem Biol Drug Des. 2018 06; 91(6):1125-1132.
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Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase. Biochemistry. 2016 06 14; 55(23):3329-40.
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Electrospray MS/MS reveals extensive and nonspecific oxidation of cholesterol esters in human peripheral vascular lesions. J Lipid Res. 2011 Nov; 52(11):2070-83.