"Captopril" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
| Descriptor ID |
D002216
|
| MeSH Number(s) |
D12.125.072.401.623.270
|
| Concept/Terms |
Captopril- Captopril
- (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
SQ-14,534- SQ-14,534
- SQ 14,534
- SQ14,534
- SQ-14534
- SQ 14534
- SQ14534
SQ-14,225- SQ-14,225
- SQ 14,225
- SQ14,225
- SQ-14225
- SQ 14225
- SQ14225
|
Below are MeSH descriptors whose meaning is more general than "Captopril".
Below are MeSH descriptors whose meaning is more specific than "Captopril".
This graph shows the total number of publications written about "Captopril" by people in this website by year, and whether "Captopril" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 4 | 0 | 4 |
| 2018 | 3 | 0 | 3 |
| 2019 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Captopril" by people in Profiles.
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Captopril alleviates lung inflammation in SARS-CoV-2-infected hypertensive mice. Zool Res. 2021 Sep 18; 42(5):633-636.
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Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers: potential allies in the COVID-19 pandemic instead of a threat? Clin Sci (Lond). 2021 04 30; 135(8):1009-1014.
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Experimental data using candesartan and captopril indicate no double-edged sword effect in COVID-19. Clin Sci (Lond). 2021 02 12; 135(3):465-481.
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Why do we lack a specific magic anti-COVID-19 drug? Analyses and solutions. Drug Discov Today. 2021 03; 26(3):631-636.
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The Use of Captopril-Angiotensin Converting Enzyme (ACE) Inhibitor for Cystinuria During COVID-19 Pandemic. Urology. 2020 07; 141:182-183.
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Comparison of the Neuroprotective Effects of Aspirin, Atorvastatin, Captopril and Metformin in Diabetes Mellitus. Biomolecules. 2019 03 27; 9(4).
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Efficacy of Zofenopril Alone or in Combination with Hydrochlorothiazide in Patients with Kidney Dysfunction. Curr Clin Pharmacol. 2019; 14(1):5-15.
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Efficacy of zofenopril in combination with amlodipine in patients with acute myocardial infarction: a pooled individual patient data analysis of four randomized, double-blind, controlled, prospective studies. Curr Med Res Opin. 2018 10; 34(10):1869-1874.
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Effects of the concomitant administration of xanthine oxidase inhibitors with zofenopril or other ACE-inhibitors in post-myocardial infarction patients: a meta-analysis of individual data of four randomized, double-blind, prospective studies. BMC Cardiovasc Disord. 2018 06 05; 18(1):112.
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Efficacy and Safety of Zofenopril Versus Ramipril in the Treatment of Myocardial Infarction and Heart Failure: A Review of the Published and Unpublished Data of the Randomized Double-Blind SMILE-4 Study. Adv Ther. 2018 May; 35(5):604-618.