"Cimetidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
| Descriptor ID |
D002927
|
| MeSH Number(s) |
D02.078.370.200 D03.383.129.308.130
|
| Concept/Terms |
Cimetidine- Cimetidine
- N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine
SK&F-92334- SK&F-92334
- SK&F 92334
- SK&F92334
- SKF-92334
- SKF 92334
- SKF92334
|
Below are MeSH descriptors whose meaning is more general than "Cimetidine".
Below are MeSH descriptors whose meaning is more specific than "Cimetidine".
This graph shows the total number of publications written about "Cimetidine" by people in this website by year, and whether "Cimetidine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cimetidine" by people in Profiles.
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Assessment of Substrate-Dependent Ligand Interactions at the Organic Cation Transporter OCT2 Using Six Model Substrates. Mol Pharmacol. 2018 09; 94(3):1057-1068.
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Multiple organic cation transporters contribute to the renal transport of sulpiride. Biopharm Drug Dispos. 2017 Dec; 38(9):526-534.
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Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat. Kidney Int. 2014 Aug; 86(2):350-7.
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Interventions for cutaneous molluscum contagiosum. Cochrane Database Syst Rev. 2009 Oct 07; (4):CD004767.