"Chenodeoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
| Descriptor ID |
D002635
|
| MeSH Number(s) |
D04.210.500.105.225.272.150 D04.210.500.221.430.342.300
|
| Concept/Terms |
Chenodeoxycholic Acid- Chenodeoxycholic Acid
- Acid, Chenodeoxycholic
- Chenique Acid
- Acid, Chenique
- Gallodesoxycholic Acid
- Acid, Gallodesoxycholic
- Henohol
- Chenic Acid
- Acid, Chenic
- Chenodiol
|
Below are MeSH descriptors whose meaning is more general than "Chenodeoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Chenodeoxycholic Acid".
This graph shows the total number of publications written about "Chenodeoxycholic Acid" by people in this website by year, and whether "Chenodeoxycholic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Chenodeoxycholic Acid" by people in Profiles.
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REGENERATE: Design of a pivotal, randomised, phase 3 study evaluating the safety and efficacy of obeticholic acid in patients with fibrosis due to nonalcoholic steatohepatitis. Contemp Clin Trials. 2019 09; 84:105803.
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Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus. Liver Int. 2019 05; 39(5):967-975.
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Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis. J Am Soc Nephrol. 2018 11; 29(11):2658-2670.
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Work in Progress: Drugs in Development. Clin Liver Dis. 2018 08; 22(3):501-515.
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Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis. Gastroenterology. 2017 09; 153(3):753-761.
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Primary Biliary Cholangitis: advances in management and treatment of the disease. Dig Liver Dis. 2017 Aug; 49(8):841-846.
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Primary biliary cholangitis in 2016: High-definition PBC: biology, models and therapeutic advances. Nat Rev Gastroenterol Hepatol. 2017 02; 14(2):76-78.
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CFTR expression but not Cl- transport is involved in the stimulatory effect of bile acids on apical Cl-/HCO3- exchange activity in human pancreatic duct cells. Pancreas. 2009 Nov; 38(8):921-9.
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A combination of chenodeoxycholic acid and ursodeoxycholic acid is more effective than either alone in reducing biliary cholesterol saturation. Hepatology. 1982 May-Jun; 2(3):334-9.