"DNA Polymerase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents. EC 2.7.7.7.
| Descriptor ID |
D004257
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.230
|
| Concept/Terms |
DNA Polymerase II- DNA Polymerase II
- DNA Polymerase epsilon
- DNA-Dependent DNA Polymerase II
- DNA Dependent DNA Polymerase II
- DNA Pol II
|
Below are MeSH descriptors whose meaning is more general than "DNA Polymerase II".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase II".
This graph shows the total number of publications written about "DNA Polymerase II" by people in this website by year, and whether "DNA Polymerase II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 1 | 2 |
| 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "DNA Polymerase II" by people in Profiles.
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POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication. Mol Cell. 2018 10 04; 72(1):112-126.e5.
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Clinical activity and safety of atezolizumab in patients with recurrent glioblastoma. J Neurooncol. 2018 Nov; 140(2):317-328.
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Genome-wide mapping of matrix attachment regions in Drosophila melanogaster. BMC Genomics. 2014 Nov 25; 15:1022.
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Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem. PLoS One. 2014; 9(9):e105729.
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Single mutations at many sites within the DNA polymerase locus of herpes simplex viruses can confer hypersensitivity to aphidicolin and resistance to phosphonoacetic acid. J Gen Virol. 1984 Jan; 65 ( Pt 1):1-17.