"Heparitin Sulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heteropolysaccharide that is similar in structure to HEPARIN. It accumulates in individuals with MUCOPOLYSACCHARIDOSIS.
| Descriptor ID |
D006497
|
| MeSH Number(s) |
D09.698.373.425
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Heparitin Sulfate".
Below are MeSH descriptors whose meaning is more specific than "Heparitin Sulfate".
This graph shows the total number of publications written about "Heparitin Sulfate" by people in this website by year, and whether "Heparitin Sulfate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 7 | 1 | 8 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 3 | 3 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heparitin Sulfate" by people in Profiles.
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Distinctive Biomarker Features in the Endotheliopathy of COVID-19 and Septic Syndromes. Shock. 2022 01 01; 57(1):95-105.
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Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate. Emerg Microbes Infect. 2021 Dec; 10(1):1065-1076.
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Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19. Proc Natl Acad Sci U S A. 2021 09 07; 118(36).
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Natural and Recombinant SARS-CoV-2 Isolates Rapidly Evolve In Vitro to Higher Infectivity through More Efficient Binding to Heparan Sulfate and Reduced S1/S2 Cleavage. J Virol. 2021 10 13; 95(21):e0135721.
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COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria. Blood. 2021 07 01; 137(26):3670-3673.
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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Cell Rep. 2021 07 13; 36(2):109364.
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From Cancer to COVID-19: A Perspective on Targeting Heparan Sulfate-Protein Interactions. Chem Rec. 2021 Nov; 21(11):3087-3101.
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Immunothrombotic dysregulation in chagas disease and COVID-19: a comparative study of anticoagulation. Mol Cell Biochem. 2021 Oct; 476(10):3815-3825.
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ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin. Cells. 2021 06 07; 10(6).
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Antiviral strategies should focus on stimulating the biosynthesis of heparan sulfates, not their inhibition. Life Sci. 2021 Jul 15; 277:119508.