"Drug Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.
| Descriptor ID |
D004361
|
| MeSH Number(s) |
G07.690.773.992
|
| Concept/Terms |
Drug Tolerance- Drug Tolerance
- Drug Tolerances
- Tolerance, Drug
- Tolerances, Drug
|
Below are MeSH descriptors whose meaning is more general than "Drug Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Drug Tolerance".
This graph shows the total number of publications written about "Drug Tolerance" by people in this website by year, and whether "Drug Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 3 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 5 | 4 | 9 |
| 2018 | 2 | 3 | 5 |
| 2019 | 0 | 4 | 4 |
| 2020 | 1 | 2 | 3 |
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Below are the most recent publications written about "Drug Tolerance" by people in Profiles.
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Steroid resistance and rebound phenomena in patients with COVID-19. Respir Investig. 2021 Sep; 59(5):608-613.
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Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial). Trials. 2020 Oct 13; 21(1):846.
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Remdesivir targets a structurally analogous region of the Ebola virus and SARS-CoV-2 polymerases. Proc Natl Acad Sci U S A. 2020 10 27; 117(43):26946-26954.
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Hydroxychloroquine and azithromycin tolerance in haemodialysis patients during COVID-19 infection. Nephrol Dial Transplant. 2020 08 01; 35(8):1346-1353.
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Acidified sodium chlorite solution: A potential prophylaxis to mitigate impact of multiple exposures to COVID-19 in frontline health-care providers. Hosp Pract (1995). 2020 Oct; 48(4):165-168.
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Thromboembolic events and apparent heparin resistance in patients infected with SARS-CoV-2. Int J Lab Hematol. 2020 06; 42 Suppl 1:19-20.
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Opioid Tolerance in Critical Illness. Reply. N Engl J Med. 2019 04 18; 380(16):e26.
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Patient Patterns and Perspectives on Using Opioid Regimens for Chronic Cancer Pain. J Pain Symptom Manage. 2019 06; 57(6):1062-1070.
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Secukinumab drug survival in patients with psoriasis: A multicenter, real-world, retrospective study. J Am Acad Dermatol. 2019 07; 81(1):273-275.
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Real-world drug survival of ixekizumab for psoriasis. J Am Acad Dermatol. 2019 07; 81(1):270-272.