Hydroxymethylglutaryl CoA Reductases
"Hydroxymethylglutaryl CoA Reductases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.
Descriptor ID |
D006903
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MeSH Number(s) |
D08.811.682.047.820.150.415
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Concept/Terms |
Hydroxymethylglutaryl CoA Reductases- Hydroxymethylglutaryl CoA Reductases
- Hydroxymethylglutaryl CoA Reductase
- HMG CoA Reductases
- 3-Hydroxy-3-methylglutaryl CoA Reductase
- 3 Hydroxy 3 methylglutaryl CoA Reductase
- CoA Reductase, 3-Hydroxy-3-methylglutaryl
- Reductase, 3-Hydroxy-3-methylglutaryl CoA
- HMG CoA Reductase
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Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl CoA Reductases".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl CoA Reductases".
This graph shows the total number of publications written about "Hydroxymethylglutaryl CoA Reductases" by people in this website by year, and whether "Hydroxymethylglutaryl CoA Reductases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 1 | 1 |
2017 | 1 | 1 | 2 |
2018 | 2 | 0 | 2 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hydroxymethylglutaryl CoA Reductases" by people in Profiles.
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Mechanisms of statin-induced new-onset diabetes. J Cell Physiol. 2019 08; 234(8):12551-12561.
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Immune-mediated necrotizing myopathy due to statins exposure. Acta Myol. 2018 Dec; 37(4):257-262.
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Necrosis in anti-SRP+ and anti-HMGCR+myopathies: Role of autoantibodies and complement. Neurology. 2018 02 06; 90(6):e507-e517.
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Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk. JAMA. 2017 09 12; 318(10):947-956.
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Analysis of genes to predict the effects of proprotein convertase subtilisin/kexin type 9-inhibitors and statins. Cardiovasc Res. 2017 05 01; 113(6):e8-e9.
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Evaluation of micro-parallel liquid chromatography as a method for HTS-coupled actives verification. Assay Drug Dev Technol. 2007 Dec; 5(6):815-24.
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Simvastatin, an inhibitor of cholesterol biosynthesis, shows a synergistic effect with N,N'-bis(2-chloroethyl)-N-nitrosourea and beta-interferon on human glioma cells. Cancer Res. 1992 Aug 15; 52(16):4348-55.