"Kynurenine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
| Descriptor ID |
D007737
|
| MeSH Number(s) |
D12.125.608
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Kynurenine".
Below are MeSH descriptors whose meaning is more specific than "Kynurenine".
This graph shows the total number of publications written about "Kynurenine" by people in this website by year, and whether "Kynurenine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2017 | 6 | 3 | 9 |
| 2018 | 4 | 7 | 11 |
| 2019 | 3 | 0 | 3 |
| 2020 | 2 | 1 | 3 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kynurenine" by people in Profiles.
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Immunometabolic signatures predict risk of progression to sepsis in COVID-19. PLoS One. 2021; 16(8):e0256784.
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Covid-19 interface with drug misuse and substance use disorders. Neuropharmacology. 2021 10 15; 198:108766.
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Gut ACE2 Expression, Tryptophan Deficiency, and Inflammatory Responses The Potential Connection That Should Not Be Ignored During SARS-CoV-2 Infection. Cell Mol Gastroenterol Hepatol. 2021; 12(4):1514-1516.e4.
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Metabolic Signatures Associated with Severity in Hospitalized COVID-19 Patients. Int J Mol Sci. 2021 Apr 30; 22(9).
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Systemic Perturbations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine Responses. J Proteome Res. 2021 05 07; 20(5):2796-2811.
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Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase inhibition? Drug Discov Today. 2021 06; 26(6):1473-1481.
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Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study. Biochim Biophys Acta Mol Basis Dis. 2021 03 01; 1867(3):166042.
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Serum neopterin levels in relation to mild and severe COVID-19. BMC Infect Dis. 2020 Dec 10; 20(1):942.
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Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide. Biosci Rep. 2020 10 30; 40(10).
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COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status. JCI Insight. 2020 07 23; 5(14).