"Interferons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
Descriptor ID |
D007372
|
MeSH Number(s) |
D12.644.276.374.440 D12.776.467.374.440 D23.529.374.440
|
Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Interferons".
Below are MeSH descriptors whose meaning is more specific than "Interferons".
This graph shows the total number of publications written about "Interferons" by people in this website by year, and whether "Interferons" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1997 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2003 | 3 | 1 | 4 |
2004 | 1 | 1 | 2 |
2005 | 1 | 0 | 1 |
2006 | 1 | 2 | 3 |
2007 | 0 | 2 | 2 |
2008 | 3 | 0 | 3 |
2009 | 1 | 3 | 4 |
2010 | 3 | 2 | 5 |
2011 | 1 | 2 | 3 |
2012 | 3 | 4 | 7 |
2013 | 3 | 4 | 7 |
2014 | 2 | 1 | 3 |
2015 | 1 | 0 | 1 |
2016 | 2 | 3 | 5 |
2017 | 31 | 37 | 68 |
2018 | 28 | 43 | 71 |
2019 | 13 | 8 | 21 |
2020 | 32 | 34 | 66 |
2021 | 15 | 29 | 44 |
To return to the timeline, click here.
Below are the most recent publications written about "Interferons" by people in Profiles.
-
Safety and immunogenicity of a recombinant interferon-armed RBD dimer vaccine (V-01) for COVID-19 in healthy adults: a randomized, double-blind, placebo-controlled, Phase I trial. Emerg Microbes Infect. 2021 Dec; 10(1):1589-1597.
-
Low incidence of COVID-19 severe complications in a large cohort of children with sickle cell disease: a protective role for basal interferon-1 activation? Haematologica. 2021 10 01; 106(10):2746-2748.
-
Ex vivo SARS-CoV-2 infection of human lung reveals heterogeneous host defense and therapeutic responses. JCI Insight. 2021 09 22; 6(18).
-
Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1. Proc Natl Acad Sci U S A. 2021 09 14; 118(37).
-
Type I, II, and III Interferon Signatures Correspond to Coronavirus Disease 2019 Severity. J Infect Dis. 2021 09 01; 224(5):777-782.
-
The early interferon catches the SARS-CoV-2. J Exp Med. 2021 10 04; 218(10).
-
Interfering with SARS-CoV-2: are interferons friends or foes in COVID-19? Curr Opin Virol. 2021 10; 50:119-127.
-
Proteomic Signature of Host Response to SARS-CoV-2 Infection in the Nasopharynx. Mol Cell Proteomics. 2021; 20:100134.
-
Luciferase reporter assays to monitor interferon signaling modulation by SARS-CoV-2 proteins. STAR Protoc. 2021 12 17; 2(4):100781.
-
IFN-?1 Displays Various Levels of Antiviral Activity In Vitro in a Select Panel of RNA Viruses. Viruses. 2021 08 12; 13(8).