"Jagged-1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC ANGIOGENESIS. Mutations in the Jagged-1 gene are associated with ALAGILLE SYNDROME 1.
| Descriptor ID |
D000072100
|
| MeSH Number(s) |
D12.644.276.930.500 D12.776.157.125.797.500 D12.776.543.800.500 D23.529.930.500
|
| Concept/Terms |
Jagged-1 Protein- Jagged-1 Protein
- Jagged 1 Protein
- Alagille Syndrome Protein
- Jagged1 Protein
- Serrate1 Protein
- Jagged-1
- Jagged 1
- Serrate-1 Protein
- Serrate 1 Protein
- CD339 Antigen
- Antigen, CD339
|
Below are MeSH descriptors whose meaning is more general than "Jagged-1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Jagged-1 Protein".
This graph shows the total number of publications written about "Jagged-1 Protein" by people in this website by year, and whether "Jagged-1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "Jagged-1 Protein" by people in Profiles.
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Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nat Neurosci. 2019 01; 22(1):91-105.
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Gremlin activates the Notch pathway linked to renal inflammation. Clin Sci (Lond). 2018 06 14; 132(11):1097-1115.
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Angiotensin II contributes to renal fibrosis independently of Notch pathway activation. PLoS One. 2012; 7(7):e40490.