"Placenta Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.
| Descriptor ID |
D000072483
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| MeSH Number(s) |
D12.644.276.100.800.100 D12.776.780.551
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Placenta Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Placenta Growth Factor".
This graph shows the total number of publications written about "Placenta Growth Factor" by people in this website by year, and whether "Placenta Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 7 | 3 | 10 |
| 2018 | 6 | 2 | 8 |
| 2019 | 0 | 2 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Placenta Growth Factor" by people in Profiles.
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Placental growth factor level in plasma predicts COVID-19 severity and in-hospital mortality. J Thromb Haemost. 2021 07; 19(7):1823-1830.
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Soluble fms-like tyrosine kinase-1: a potential early predictor of respiratory failure in COVID-19 patients. Clin Chem Lab Med. 2021 06 25; 59(7):e289-e292.
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SFLT-1 levels in COVID-19 patients: Association with outcome and thrombosis. Am J Hematol. 2021 02 01; 96(2):E41-E43.
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Antiviral properties of placental growth factors: A novel therapeutic approach for COVID-19 treatment. Placenta. 2020 09 15; 99:117-130.
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Increased sFLT-1/PlGF ratio in COVID-19: A novel link to angiotensin II-mediated endothelial dysfunction. Am J Hematol. 2020 08; 95(8):E188-E191.
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Pre-eclampsia-like syndrome induced by severe COVID-19: a prospective observational study. BJOG. 2020 10; 127(11):1374-1380.
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Management of pregnancy blood pressure increase in the emergency room: role of PlGF-based biochemical markers and relative economic impact. J Matern Fetal Neonatal Med. 2021 Apr; 34(7):1083-1090.
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Postpartum blood pressure patterns in severe preeclampsia and normotensive pregnant women following abdominal deliveries: a cohort study. J Matern Fetal Neonatal Med. 2020 Sep; 33(18):3152-3162.
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The Use of Soluble FMS-like Tyrosine Kinase 1/Placental Growth Factor Ratio in the Clinical Management of Pre-eclampsia. Afr J Reprod Health. 2018 Dec; 22(4):135-143.
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Brain angiogenic gene expression in fetuses with congenital heart disease. Ultrasound Obstet Gynecol. 2018 Dec; 52(6):734-738.