"Replicon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any DNA sequence capable of independent replication or a molecule that possesses a REPLICATION ORIGIN and which is therefore potentially capable of being replicated in a suitable cell. (Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
| Descriptor ID |
D012093
|
| MeSH Number(s) |
G05.360.340.024.745
|
| Concept/Terms |
Replicon- Replicon
- Replicons
- Replication Unit
- Replication Units
- Unit, Replication
- Units, Replication
|
Below are MeSH descriptors whose meaning is more general than "Replicon".
Below are MeSH descriptors whose meaning is more specific than "Replicon".
This graph shows the total number of publications written about "Replicon" by people in this website by year, and whether "Replicon" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2008 | 2 | 1 | 3 |
| 2010 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 6 | 7 |
| 2018 | 2 | 7 | 9 |
| 2019 | 0 | 1 | 1 |
| 2020 | 3 | 0 | 3 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Replicon" by people in Profiles.
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Construction of a Noninfectious SARS-CoV-2 Replicon for Antiviral-Drug Testing and Gene Function Studies. J Virol. 2021 08 25; 95(18):e0068721.
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A Convenient and Biosafe Replicon with Accessory Genes of SARS-CoV-2 and Its Potential Application in Antiviral Drug Discovery. Virol Sin. 2021 Oct; 36(5):913-923.
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SARS-CoV-2 replicon for high-throughput antiviral screening. J Gen Virol. 2021 05; 102(5).
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Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing. Proc Natl Acad Sci U S A. 2021 04 13; 118(15).
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Construction of Non-infectious SARS-CoV-2 Replicons and Their Application in Drug Evaluation. Virol Sin. 2021 Oct; 36(5):890-900.
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A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice. Mol Ther. 2021 06 02; 29(6):1970-1983.
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Self-Amplifying Pestivirus Replicon RNA Encoding Influenza Virus Nucleoprotein and Hemagglutinin Promote Humoral and Cellular Immune Responses in Pigs. Front Immunol. 2020; 11:622385.
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Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors. mBio. 2021 01 19; 12(1).
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A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2. Antiviral Res. 2021 01; 185:104974.
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A mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon particles. Cell Res. 2020 11; 30(11):1046-1048.