Purpura, Thrombotic Thrombocytopenic
"Purpura, Thrombotic Thrombocytopenic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE.
| Descriptor ID |
D011697
|
| MeSH Number(s) |
C15.378.100.802.687.680 C15.378.140.855.925.750.680 C15.378.925.850 C23.550.414.950.687.680 C23.888.885.687.687.680
|
| Concept/Terms |
Purpura, Thrombotic Thrombocytopenic- Purpura, Thrombotic Thrombocytopenic
- Thrombocytopenic Purpura, Thrombotic
- Moschkowitz Disease
- Disease, Moschkowitz
- Thrombotic Thrombocytopenic Purpura
- Moschcowitz Disease
- Disease, Moschcowitz
- Purpura, Thrombotic Thrombopenic
- Thrombopenic Purpura, Thrombotic
- Thrombotic Thrombopenic Purpura
Congenital Thrombotic Thrombocytopenic Purpura- Congenital Thrombotic Thrombocytopenic Purpura
- Schulman-Upshaw Syndrome
- Schulman Upshaw Syndrome
- Syndrome, Schulman-Upshaw
- Upshaw-Schulman Syndrome
- Syndrome, Upshaw-Schulman
- Upshaw Schulman Syndrome
- Thrombotic Thrombocytopenic Purpura, Congenital
- Upshaw Factor, Deficiency of
- Microangiopathic Hemolytic Anemia, Congenital
- Thrombotic Microangiopathy, Familial
- Familial Thrombotic Microangiopathy
- Microangiopathy, Familial Thrombotic
|
Below are MeSH descriptors whose meaning is more general than "Purpura, Thrombotic Thrombocytopenic".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Blood Coagulation Disorders [C15.378.100]
- Purpura [C15.378.100.802]
- Purpura, Thrombocytopenic [C15.378.100.802.687]
- Purpura, Thrombotic Thrombocytopenic [C15.378.100.802.687.680]
- Blood Platelet Disorders [C15.378.140]
- Thrombocytopenia [C15.378.140.855]
- Thrombotic Microangiopathies [C15.378.140.855.925]
- Purpura, Thrombocytopenic [C15.378.140.855.925.750]
- Purpura, Thrombotic Thrombocytopenic [C15.378.140.855.925.750.680]
- Thrombophilia [C15.378.925]
- Purpura, Thrombotic Thrombocytopenic [C15.378.925.850]
- Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
- Hemorrhage [C23.550.414]
- Purpura [C23.550.414.950]
- Purpura, Thrombocytopenic [C23.550.414.950.687]
- Purpura, Thrombotic Thrombocytopenic [C23.550.414.950.687.680]
- Signs and Symptoms [C23.888]
- Skin Manifestations [C23.888.885]
- Purpura [C23.888.885.687]
- Purpura, Thrombocytopenic [C23.888.885.687.687]
- Purpura, Thrombotic Thrombocytopenic [C23.888.885.687.687.680]
Below are MeSH descriptors whose meaning is more specific than "Purpura, Thrombotic Thrombocytopenic".
This graph shows the total number of publications written about "Purpura, Thrombotic Thrombocytopenic" by people in this website by year, and whether "Purpura, Thrombotic Thrombocytopenic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 7 | 2 | 9 |
| 2018 | 11 | 3 | 14 |
| 2019 | 3 | 1 | 4 |
| 2020 | 1 | 0 | 1 |
| 2021 | 10 | 0 | 10 |
To return to the timeline, click here.
Below are the most recent publications written about "Purpura, Thrombotic Thrombocytopenic" by people in Profiles.
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Clinical Characteristics and Pharmacological Management of COVID-19 Vaccine-Induced Immune Thrombotic Thrombocytopenia With Cerebral Venous Sinus Thrombosis: A Review. JAMA Cardiol. 2021 12 01; 6(12):1451-1460.
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Hematologic autoimmune disorders in the course of COVID-19: a systematic review of reported cases. Hematology. 2021 Dec; 26(1):225-239.
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Thrombotic thrombocytopenic purpura temporally associated with BNT162b2 vaccination in an adolescent successfully treated with caplacizumab. Br J Haematol. 2022 01; 196(1):e11-e14.
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Transplantation Outcome in Recipients Engrafted With Organs Recovered From the First French Deceased Donor With a SARS-COV-2 Vaccine-induced Thrombotic Thrombocytopenia. Transplantation. 2021 08 01; 105(8):e84-e86.
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Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2. Blood. 2021 07 29; 138(4):299-303.
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Imbalance of von Willebrand factor and ADAMTS13 axis is rather a biomarker of strong inflammation and endothelial damage than a cause of thrombotic process in critically ill COVID-19 patients. J Thromb Haemost. 2021 09; 19(9):2193-2198.
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Acquired thrombotic thrombocytopenic purpura after first vaccination dose of BNT162b2 mRNA COVID-19 vaccine. Ann Hematol. 2022 03; 101(3):717-719.
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Thrombotic thrombocytopenic purpura: a new menace after COVID bnt162b2 vaccine. Int J Hematol. 2021 Nov; 114(5):626-629.
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Acquired thrombotic thrombocytopenic purpura: A rare disease associated with BNT162b2 vaccine. J Thromb Haemost. 2021 09; 19(9):2314-2317.
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First report of a de novo iTTP episode associated with an mRNA-based anti-COVID-19 vaccination. J Thromb Haemost. 2021 08; 19(8):2014-2018.