"Factor V" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.
| Descriptor ID |
D005165
|
| MeSH Number(s) |
D12.776.124.125.300 D23.119.300
|
| Concept/Terms |
Factor V- Factor V
- Factor Five
- Five, Factor
- AC Globulin
- Blood Coagulation Factor V
- Factor Pi
- Proaccelerin
- Factor 5
- Coagulation Factor V
- Factor V, Coagulation
|
Below are MeSH descriptors whose meaning is more general than "Factor V".
Below are MeSH descriptors whose meaning is more specific than "Factor V".
This graph shows the total number of publications written about "Factor V" by people in this website by year, and whether "Factor V" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 3 | 1 | 4 |
| 2019 | 5 | 2 | 7 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Factor V" by people in Profiles.
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Acquired factor V inhibitor in the setting of coronavirus disease 2019 infection. Blood Coagul Fibrinolysis. 2021 Jun 01; 32(4):294-297.
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Elevated factor V activity and antigen levels in patients with Covid-19 are related to disease severity and 30-day mortality. Am J Hematol. 2021 04 01; 96(4):E98-E100.
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Marked factor V activity elevation in severe COVID-19 is associated with venous thromboembolism. Am J Hematol. 2020 12; 95(12):1522-1530.
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Imbalance between procoagulant factors and natural coagulation inhibitors contributes to hypercoagulability in the critically ill COVID-19 patient: clinical implications. Eur Rev Med Pharmacol Sci. 2020 Sep; 24(17):9161-9168.
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Genetic Testing for Thrombophilia-Related Genes: Observations of Testing Patterns for Factor V Leiden (G1691A) and Prothrombin Gene "Mutation" (G20210A). Semin Thromb Hemost. 2019 Oct; 45(7):730-742.
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Profiling the mutational landscape of coagulation factor V deficiency. Haematologica. 2020 04; 105(4):e180-e185.
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An "unmodifiable" risk factor that has been modified. Intern Emerg Med. 2021 01; 16(1):157-159.
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Lipase and factor V (but not viral load) are prognostic factors for the evolution of severe yellow fever cases. Mem Inst Oswaldo Cruz. 2019; 114:e190033.
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Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity. J Exp Med. 2019 06 03; 216(6):1291-1300.
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Successful management of transcatheter aortic valve implantation by platelet transfusions in a nonagenarian patient with severe autoimmune factor V deficiency. Ann Hematol. 2019 Aug; 98(8):1991-1992.