"Physostigmine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Descriptor ID |
D010830
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MeSH Number(s) |
D02.241.081.251.583.682 D03.132.436.545 D03.633.100.473.402.545
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Physostigmine".
Below are MeSH descriptors whose meaning is more specific than "Physostigmine".
This graph shows the total number of publications written about "Physostigmine" by people in this website by year, and whether "Physostigmine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 2 | 1 | 3 |
2018 | 2 | 0 | 2 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Physostigmine" by people in Profiles.
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Effect of physostigmine on recovery from septic shock following intra-abdominal infection - Results from a randomized, double-blind, placebo-controlled, monocentric pilot trial (Anticholium® per Se). J Crit Care. 2019 08; 52:126-135.
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In-depth characterization of the neuroinflammatory reaction induced by peripheral surgery in an animal model. J Neural Transm (Vienna). 2018 10; 125(10):1487-1494.
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Physostigmine Restores Impaired Autophagy in the Rat Hippocampus after Surgery Stress and LPS Treatment. J Neuroimmune Pharmacol. 2018 09; 13(3):383-395.
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Adjunctive use of physostigmine salicylate (Anticholium®) in perioperative sepsis and septic shock: study protocol for a randomized, double-blind, placebo-controlled, monocentric trial (Anticholium® per Se). Trials. 2017 Nov 10; 18(1):530.
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Behavioral and biochemical evidences for nootropic activity of boldine in young and aged mice. Biomed Pharmacother. 2018 Jan; 97:895-904.
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Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer's Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses. CNS Neurol Disord Drug Targets. 2017; 16(7):820-827.