"Complement C4b" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
| Descriptor ID |
D015935
|
| MeSH Number(s) |
D12.776.124.486.274.350.260
|
| Concept/Terms |
Complement C4b- Complement C4b
- C4b, Complement
- Complement 4b
- Complement Component 4b
- Component 4b, Complement
- C4b Complement
- Complement, C4b
|
Below are MeSH descriptors whose meaning is more general than "Complement C4b".
Below are MeSH descriptors whose meaning is more specific than "Complement C4b".
This graph shows the total number of publications written about "Complement C4b" by people in this website by year, and whether "Complement C4b" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 4 | 1 | 5 |
| 2018 | 0 | 2 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Complement C4b" by people in Profiles.
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Diffuse C4d staining of peritubular capillaries in renal allograft following bamlanivimab therapy. Am J Transplant. 2022 01; 22(1):289-293.
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Erythrocytes identify complement activation in patients with COVID-19. Am J Physiol Lung Cell Mol Physiol. 2021 08 01; 321(2):L485-L489.
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Acquired decrease of the C3b/C4b receptor (CR1, CD35) and increased C4d deposits on erythrocytes from ICU COVID-19 patients. Immunobiology. 2021 05; 226(3):152093.
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Livedo reticularis and acrocyanosis as late manifestations of COVID-19 in two cases with familial aggregation. Potential pathogenic role of complement (C4c). Int J Dermatol. 2020 Dec; 59(12):1549-1551.
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Anti-complement C5 therapy with eculizumab in three cases of critical COVID-19. Clin Immunol. 2020 10; 219:108555.
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Tofacitinib Halts Progression of Graft Dysfunction in a Rat Model of Mixed Cellular and Humoral Rejection. Transplantation. 2018 07; 102(7):1075-1084.
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Prognostic Value of the Persistence of C1q-Binding Anti-HLA Antibodies in Acute Antibody-Mediated Rejection in Kidney Transplantation. Transplantation. 2018 04; 102(4):688-698.
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Global quality assessment of liver allograft C4d staining during acute antibody-mediated rejection in formalin-fixed, paraffin-embedded tissue. Hum Pathol. 2018 03; 73:144-155.
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Plasma Levels of Complement Factor I and C4b Peptides Are Associated with HIV Suppression. ACS Infect Dis. 2017 12 08; 3(12):880-885.
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Persistent C4d and antibody-mediated rejection in pediatric renal transplant patients. Pediatr Transplant. 2017 Nov; 21(7).