Receptors, Antigen, T-Cell, alpha-beta
"Receptors, Antigen, T-Cell, alpha-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.
| Descriptor ID |
D016693
|
| MeSH Number(s) |
D12.776.543.750.705.816.824.825
|
| Concept/Terms |
Receptors, Antigen, T-Cell, alpha-beta- Receptors, Antigen, T-Cell, alpha-beta
- Antigen Receptors, T-Cell, alpha-beta
- TcR alpha-beta
- TcR alpha beta
- alpha-beta, TcR
- T-Cell Receptor, alpha-beta
- T Cell Receptor, alpha beta
- alpha-beta T-Cell Receptor
- T-Cell Receptors, alpha-beta
- alpha-beta T-Cell Receptors
- Receptors, Antigen, T Cell, alpha beta
- T Cell Receptors, alpha beta
Antigen T Cell Receptor, beta Chain- Antigen T Cell Receptor, beta Chain
- T-Cell Receptors beta-Chain
- T Cell Receptors beta Chain
- beta-Chain, T-Cell Receptors
- T-Cell Receptor beta-Chain
- T Cell Receptor beta Chain
- beta-Chain, T-Cell Receptor
T-Cell Receptors alpha-Chain- T-Cell Receptors alpha-Chain
- T Cell Receptors alpha Chain
- alpha-Chain, T-Cell Receptors
- Antigen T Cell Receptor, alpha Chain
- T-Cell Receptor alpha-Chain
- T Cell Receptor alpha Chain
- alpha-Chain, T-Cell Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, T-Cell, alpha-beta".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]
- Receptors, Antigen, T-Cell, alpha-beta [D12.776.543.750.705.816.824.825]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, T-Cell, alpha-beta".
This graph shows the total number of publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in this website by year, and whether "Receptors, Antigen, T-Cell, alpha-beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 5 | 4 | 9 |
| 2018 | 6 | 5 | 11 |
| 2019 | 5 | 0 | 5 |
| 2021 | 2 | 2 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in Profiles.
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Human CD4+ T cells specific for dominant epitopes of SARS-CoV-2 Spike and Nucleocapsid proteins with therapeutic potential. Clin Exp Immunol. 2021 09; 205(3):363-378.
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Polyclonal expansion of TCR Vbeta 21.3+ CD4+ and CD8+ T cells is a hallmark of Multisystem Inflammatory Syndrome in Children. Sci Immunol. 2021 05 25; 6(59).
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Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2. Science. 2021 06 18; 372(6548):1336-1341.
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HLA class I-associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children. J Clin Invest. 2021 05 17; 131(10).
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CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity. Immunity. 2021 05 11; 54(5):1066-1082.e5.
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TRB sequences targeting ORF1a/b are associated with disease severity in hospitalized COVID-19 patients. J Leukoc Biol. 2022 01; 111(1):283-289.
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High-Throughput Immunogenetics Reveals a Lack of Physiological T Cell Clusters in Patients With Autoimmune Cytopenias. Front Immunol. 2019; 10:1897.
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The Identity Card of T Cells-Clinical Utility of T-cell Receptor Repertoire Analysis in Transplantation. Transplantation. 2019 08; 103(8):1544-1555.
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T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy. Br J Haematol. 2019 10; 187(2):206-218.
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Shorter TCR ß-Chains Are Highly Enriched During Thymic Selection and Antigen-Driven Selection. Front Immunol. 2019; 10:299.