"Adenosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
| Descriptor ID |
D000241
|
| MeSH Number(s) |
D03.633.100.759.590.138 D13.570.583.138 D13.570.800.096
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Adenosine".
Below are MeSH descriptors whose meaning is more specific than "Adenosine".
This graph shows the total number of publications written about "Adenosine" by people in this website by year, and whether "Adenosine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 2 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 26 | 20 | 46 |
| 2018 | 8 | 17 | 25 |
| 2019 | 4 | 8 | 12 |
| 2020 | 1 | 8 | 9 |
| 2021 | 4 | 7 | 11 |
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Below are the most recent publications written about "Adenosine" by people in Profiles.
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In silico identification of novel SARS-COV-2 2'-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):727-736.
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DAMPening COVID-19 Severity by Attenuating Danger Signals. Front Immunol. 2021; 12:720192.
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Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2. Bioorg Med Chem. 2021 09 15; 46:116364.
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Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs. Antimicrob Agents Chemother. 2021 09 17; 65(10):e0115521.
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Quantitative HPLC-MS/MS determination of Nuc, the active metabolite of remdesivir, and its pharmacokinetics in rat. Anal Bioanal Chem. 2021 Sep; 413(23):5811-5820.
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Pharmacokinetics of Remdesivir and GS-441524 during PIRRT and Seraph 100 Therapy. Clin J Am Soc Nephrol. 2021 08; 16(8):1256-1257.
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RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes. Cell Death Dis. 2021 07 23; 12(8):732.
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Cellular Uptake and Intracellular Phosphorylation of GS-441524: Implications for Its Effectiveness against COVID-19. Viruses. 2021 07 14; 13(7).
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Methyltransferase-like 3 Modulates Severe Acute Respiratory Syndrome Coronavirus-2 RNA N6-Methyladenosine Modification and Replication. mBio. 2021 08 31; 12(4):e0106721.
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In vitro activity of itraconazole against SARS-CoV-2. J Med Virol. 2021 Jul; 93(7):4454-4460.