"Immediate-Early Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
| Descriptor ID |
D017874
|
| MeSH Number(s) |
D12.776.460 D12.776.964.925.968
|
| Concept/Terms |
Immediate-Early Proteins- Immediate-Early Proteins
- Immediate Early Proteins
- Proteins, Immediate-Early
- Proteins, Immediate Early
|
Below are MeSH descriptors whose meaning is more general than "Immediate-Early Proteins".
Below are MeSH descriptors whose meaning is more specific than "Immediate-Early Proteins".
This graph shows the total number of publications written about "Immediate-Early Proteins" by people in this website by year, and whether "Immediate-Early Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 5 | 5 | 10 |
| 2018 | 5 | 4 | 9 |
| 2019 | 2 | 1 | 3 |
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Below are the most recent publications written about "Immediate-Early Proteins" by people in Profiles.
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Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19. Med Hypotheses. 2020 Nov; 144:110237.
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Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis. J Infect Dis. 2019 09 13; 220(8):1302-1306.
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Erythropoietin inhibits SGK1-dependent TH17 induction and TH17-dependent kidney disease. JCI Insight. 2019 04 23; 5.
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The isoquinoline alkaloid berberine inhibits human cytomegalovirus replication by interfering with the viral Immediate Early-2 (IE2) protein transactivating activity. Antiviral Res. 2019 04; 164:52-60.
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Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells. Front Immunol. 2018; 9:2539.
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mTOR- and SGK-Mediated Connexin 43 Expression Participates in Lipopolysaccharide-Stimulated Macrophage Migration through the iNOS/Src/FAK Axis. J Immunol. 2018 11 15; 201(10):2986-2997.
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Attenuated Herpes Simplex Virus 1 (HSV-1) Expressing a Mutant Form of ICP6 Stimulates a Strong Immune Response That Protects Mice against HSV-1-Induced Corneal Disease. J Virol. 2018 09 01; 92(17).
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Human Cytomegalovirus Immediate Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus. J Virol. 2018 09 01; 92(17).
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SGK1 induces vascular smooth muscle cell calcification through NF-?B signaling. J Clin Invest. 2018 07 02; 128(7):3024-3040.
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Caspase-Dependent Apoptosis Induction via Viral Protein ORF4 of Porcine Circovirus 2 Binding to Mitochondrial Adenine Nucleotide Translocase 3. J Virol. 2018 05 15; 92(10).