"Patch-Clamp Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
| Descriptor ID |
D018408
|
| MeSH Number(s) |
E05.200.500.905 E05.242.800
|
| Concept/Terms |
Patch-Clamp Techniques- Patch-Clamp Techniques
- Patch Clamp Techniques
- Patch-Clamp Technique
- Technique, Patch-Clamp
- Techniques, Patch-Clamp
- Patch-Clamp Technics
- Patch Clamp Technics
- Patch-Clamp Technic
- Technic, Patch-Clamp
- Technics, Patch-Clamp
Whole-Cell Recording- Whole-Cell Recording
- Recording, Whole-Cell
- Recordings, Whole-Cell
- Whole Cell Recording
- Whole-Cell Recordings
Voltage-Clamp Techniques- Voltage-Clamp Techniques
- Technique, Voltage-Clamp
- Techniques, Voltage-Clamp
- Voltage Clamp Techniques
- Voltage-Clamp Technique
- Voltage-Clamp Technics
- Technic, Voltage-Clamp
- Technics, Voltage-Clamp
- Voltage Clamp Technics
- Voltage-Clamp Technic
|
Below are MeSH descriptors whose meaning is more general than "Patch-Clamp Techniques".
Below are MeSH descriptors whose meaning is more specific than "Patch-Clamp Techniques".
This graph shows the total number of publications written about "Patch-Clamp Techniques" by people in this website by year, and whether "Patch-Clamp Techniques" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 3 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 9 | 10 |
| 2018 | 0 | 8 | 8 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Patch-Clamp Techniques" by people in Profiles.
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Computational and experimental studies on the inhibitory mechanism of hydroxychloroquine on hERG. Toxicology. 2021 06 30; 458:152822.
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Antiviral Drug Ivermectin at Nanomolar Concentrations Inhibits Glycine-Induced Chloride Current in Rat Hippocampal Neurons. Bull Exp Biol Med. 2021 Mar; 170(5):649-653.
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Classification of electrophysiological and morphological neuron types in the mouse visual cortex. Nat Neurosci. 2019 07; 22(7):1182-1195.
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Syncytial isopotentiality: A system-wide electrical feature of astrocytic networks in the brain. Glia. 2018 12; 66(12):2756-2769.
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Dexmedetomidine relieves neuropathic pain by inhibiting hyperpolarization-activated cyclic nucleotide-gated currents in dorsal root ganglia neurons. Neuroreport. 2018 08 15; 29(12):1001-1006.
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Reversal of dopamine-mediated firing inhibition through activation of the dopamine transporter in substantia nigra pars compacta neurons. Br J Pharmacol. 2018 09; 175(17):3534-3547.
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Verapamil Inhibits TRESK (K2P18.1) Current in Trigeminal Ganglion Neurons Independently of the Blockade of Ca2+ Influx. Int J Mol Sci. 2018 07 04; 19(7).
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A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. Elife. 2018 06 20; 7.
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a-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease. Nat Commun. 2018 06 12; 9(1):2293.
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Enhancement of 5-HT2A receptor function and blockade of Kv1.5 by MK801 and ketamine: implications for PCP derivative-induced disease models. Exp Mol Med. 2018 04 27; 50(4):1-8.