Clinical Trials Data Monitoring Committees
"Clinical Trials Data Monitoring Committees" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Committees established to review interim data and efficacy outcomes in clinical trials. The findings of these committees are used in deciding whether a trial should be continued as designed, changed, or terminated. Government regulations regarding federally-funded research involving human subjects (the "Common Rule") require (45 CFR 46.111) that research ethics committees reviewing large-scale clinical trials monitor the data collected using a mechanism such as a data monitoring committee. FDA regulations (21 CFR 50.24) require that such committees be established to monitor studies conducted in emergency settings.
| Descriptor ID |
D026661
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| MeSH Number(s) |
N05.700.685.149
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| Concept/Terms |
Clinical Trials Data Monitoring Committees- Clinical Trials Data Monitoring Committees
- Data Monitoring Committees
- Committee, Data Monitoring
- Committees, Data Monitoring
- Data Monitoring Committee
- Monitoring Committee, Data
- Monitoring Committees, Data
- Safety Monitoring Boards
- Board, Safety Monitoring
- Boards, Safety Monitoring
- Monitoring Board, Safety
- Monitoring Boards, Safety
- Safety Monitoring Board
- Data and Safety Monitoring Boards
|
Below are MeSH descriptors whose meaning is more general than "Clinical Trials Data Monitoring Committees".
Below are MeSH descriptors whose meaning is more specific than "Clinical Trials Data Monitoring Committees".
This graph shows the total number of publications written about "Clinical Trials Data Monitoring Committees" by people in this website by year, and whether "Clinical Trials Data Monitoring Committees" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 3 | 0 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clinical Trials Data Monitoring Committees" by people in Profiles.
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Behind the Scenes Heroes: The COVID-19 Vaccine Data and Safety Monitoring Board. J Infect Dis. 2021 12 15; 224(12):1993-1994.
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The Essential Role of Data and Safety Monitoring Boards (DSMBs) in Ensuring the Ethics of Global Vaccine Trials to Address Coronavirus Disease 2019 (COVID-19O). Clin Infect Dis. 2021 12 06; 73(11):2126-2130.
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Risk-based centralized data monitoring of clinical trials at the time of COVID-19 pandemic. Contemp Clin Trials. 2021 05; 104:106368.
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Clinical trials in a COVID-19 pandemic: Shared infrastructure for continuous learning in a rapidly changing landscape. Clin Trials. 2021 06; 18(3):324-334.
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Research on COVID-19: Stories from IRB Members, Research Administrators, & Investigators. Narrat Inq Bioeth. 2021; 11(1):74-76.
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Moving fast but going slow: coordination challenges for trials of COVID-19 post-exposure prophylaxis. Trials. 2020 Sep 29; 21(1):815.
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Data monitoring committees for clinical trials evaluating treatments of COVID-19. Contemp Clin Trials. 2020 11; 98:106154.
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It is unprecedented: trial management during the COVID-19 pandemic and beyond. Trials. 2020 Sep 11; 21(1):784.
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[Data monitoring committees-state of the art and perspectives for the future]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Dec; 63(12):1511-1518.
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Achieving effective informed oversight by DMCs in COVID clinical trials. J Clin Epidemiol. 2020 10; 126:167-171.