"Hybridomas" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.
| Descriptor ID |
D006825
|
| MeSH Number(s) |
A11.251.353.485 A11.251.600.485
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hybridomas".
Below are MeSH descriptors whose meaning is more specific than "Hybridomas".
This graph shows the total number of publications written about "Hybridomas" by people in this website by year, and whether "Hybridomas" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2006 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 9 | 10 |
| 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "Hybridomas" by people in Profiles.
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Rapid and reliable hybridoma screening method that is suitable for production of functional structure-recognizing monoclonal antibody. J Biosci Bioeng. 2021 Jun; 131(6):696-702.
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Establishment of Murine Hybridoma Cells Producing Antibodies against Spike Protein of SARS-CoV-2. Int J Mol Sci. 2020 Dec 01; 21(23).
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Production and characterization of monoclonal antibodies specific for major capsid VP1 protein of trichodysplasia spinulosa-associated polyomavirus. Microbiol Immunol. 2018 Dec; 62(12):763-773.
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Production of a monoclonal antibody against a mannose-binding protein of Acanthamoeba culbertsoni and its localization. Exp Parasitol. 2018 Sep; 192:19-24.
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A Rapid Method for Antigen-Specific Hybridoma Clone Isolation. Anal Chem. 2018 02 06; 90(3):2224-2229.
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Structural and Functional Characterization of a Cross-Reactive Dengue Virus Neutralizing Antibody that Recognizes a Cryptic Epitope. Structure. 2018 01 02; 26(1):51-59.e4.
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Novel BAFF-Receptor Antibody to Natively Folded Recombinant Protein Eliminates Drug-Resistant Human B-cell Malignancies In Vivo. Clin Cancer Res. 2018 03 01; 24(5):1114-1123.
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Nanomagnetic System for Rapid Diagnosis of Acute Infection. ACS Nano. 2017 11 28; 11(11):11425-11432.
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5B9, a monoclonal antiplatelet factor 4/heparin IgG with a human Fc fragment that mimics heparin-induced thrombocytopenia antibodies. J Thromb Haemost. 2017 10; 15(10):2065-2075.
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Improved antibody-based ricin neutralization by affinity maturation is correlated with slower off-rate values. Protein Eng Des Sel. 2017 09 01; 30(9):611-617.