"Paraproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormal immunoglobulins synthesized by atypical cells of the MONONUCLEAR PHAGOCYTE SYSTEM. Paraproteins containing only light chains lead to Bence Jones paraproteinemia, while the presence of only atypical heavy chains leads to heavy chain disease. Most of the paraproteins show themselves as an M-component (monoclonal gammopathy) in electrophoresis. Diclonal and polyclonal paraproteins are much less frequently encountered.
| Descriptor ID |
D010266
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| MeSH Number(s) |
D12.776.124.486.485.900 D12.776.124.790.651.900 D12.776.377.715.548.900
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Paraproteins".
Below are MeSH descriptors whose meaning is more specific than "Paraproteins".
This graph shows the total number of publications written about "Paraproteins" by people in this website by year, and whether "Paraproteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Paraproteins" by people in Profiles.
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A clone-directed approach may improve diagnosis and treatment of proliferative glomerulonephritis with monoclonal immunoglobulin deposits. Kidney Int. 2018 07; 94(1):199-205.
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The serum heavy/light chain immunoassay: A valuable tool for sensitive paraprotein assessment, risk, and disease monitoring in monoclonal gammopathies. Eur J Haematol. 2017 Nov; 99(5):449-458.
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On the path to evidence-based reporting of serum protein electrophoresis patterns in the absence of a discernible monoclonal protein - A critical review of literature and practice suggestions. Clin Biochem. 2018 Jan; 51:29-37.