"4-1BB Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.
| Descriptor ID |
D053330
|
| MeSH Number(s) |
D12.644.276.374.750.065 D12.776.395.192 D12.776.467.374.750.065 D12.776.543.550.194 D23.529.374.750.065
|
| Concept/Terms |
4-1BB Ligand- 4-1BB Ligand
- 4 1BB Ligand
- Tumor Necrosis Factor Ligand Superfamily Member 9
- Tumor Necrosis Factor (Ligand) Superfamily, Member 9
- 4-1BBL Protein
- 4 1BBL Protein
- CD137 Ligand
|
Below are MeSH descriptors whose meaning is more general than "4-1BB Ligand".
Below are MeSH descriptors whose meaning is more specific than "4-1BB Ligand".
This graph shows the total number of publications written about "4-1BB Ligand" by people in this website by year, and whether "4-1BB Ligand" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "4-1BB Ligand" by people in Profiles.
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Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab. Cell Rep. 2018 10 23; 25(4):909-920.e4.
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4-1BBL enhances CD8+ T cell responses induced by vectored vaccines in mice but fails to improve immunogenicity in rhesus macaques. PLoS One. 2014; 9(8):e105520.
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Protein transfer enhances cellular immune responses to DNA vaccination against SARS-CoV. Viral Immunol. 2009 Dec; 22(6):417-22.
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CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice. Circulation. 2008 Mar 11; 117(10):1292-301.