"Puromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
| Descriptor ID |
D011691
|
| MeSH Number(s) |
D02.241.223.200.380 D03.633.100.759.590.138.711 D09.408.051.788 D13.570.583.138.711
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Puromycin".
Below are MeSH descriptors whose meaning is more specific than "Puromycin".
This graph shows the total number of publications written about "Puromycin" by people in this website by year, and whether "Puromycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Puromycin" by people in Profiles.
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A New Photocaged Puromycin for an Efficient Labeling of Newly Translated Proteins in Living Neurons. Chembiochem. 2018 12 04; 19(23):2458-2464.
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Development and RNA-synthesizing activity of coronavirus replication structures in the absence of protein synthesis. J Virol. 2011 Jun; 85(11):5669-73.
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In vitro replication of mouse hepatitis virus strain A59. J Virol. 1987 Jun; 61(6):1814-20.
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Enhancing effect of the murine sarcoma virus (MSV) on the replication of the mouse hepatitis virus (MHV) in vitro. Proc Soc Exp Biol Med. 1969 May; 131(1):30-5.
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Studies on the mechanism of destruction of lymphoid tissue in murine hepatitis virus (MHV3) infection. I. Selective prevention of lymphoid necrosis by cortisone and puromycin. Lab Invest. 1966 Jan; 15(1 Pt 2):270-82.