"Chemokine CX3CL1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of chemokine CX3CL1 can be released from cell surface by proteolysis and act as a chemoattractant that may be involved in the extravasation of leukocytes into inflamed tissues. The membrane form of the protein may also play a role in cell adhesion.
Descriptor ID |
D054428
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MeSH Number(s) |
D12.644.276.374.200.130.500 D12.776.467.374.200.130.500 D12.776.543.193 D23.125.300.130.500 D23.469.200.130.500 D23.529.374.200.130.500
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Concept/Terms |
Chemokine CX3CL1- Chemokine CX3CL1
- CX3CL1, Chemokine
- CX3CL1 Chemokine
- Chemokine, CX3CL1
- Neurotactin
- Chemokine (C-X3-C Motif) Ligand 1
- Fractalkine
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Below are MeSH descriptors whose meaning is more general than "Chemokine CX3CL1".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CX3CL1".
This graph shows the total number of publications written about "Chemokine CX3CL1" by people in this website by year, and whether "Chemokine CX3CL1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2017 | 2 | 1 | 3 |
2018 | 3 | 3 | 6 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chemokine CX3CL1" by people in Profiles.
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Could SARS-CoV-2 blocking of ACE2 in endothelial cells result in upregulation of CX3CL1, promoting thrombosis in COVID-19 patients? Med Hypotheses. 2021 Jun; 151:110570.
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Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients. J Infect Dis. 2020 08 17; 222(6):894-898.
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Circulating CXCR3-CCR6-CXCR5+CD4+ T cells are associated with acute allograft rejection in liver transplantation. Immunol Lett. 2019 09; 213:55-61.
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Involvement of stromal cell-derived factor-1a (SDF-1a), stem cell factor (SCF), fractalkine (FKN) and VEGF in TSG protection against intimal hyperplasia in rat balloon injury. Biomed Pharmacother. 2019 Feb; 110:887-894.
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IP3-Mediated Calcium Signaling Is Involved in the Mechanism of Fractalkine-Induced Hyperalgesia Response. Med Sci Monit. 2018 Dec 05; 24:8804-8811.
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Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis. PLoS One. 2018; 13(11):e0206545.
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Work in Progress: Drugs in Development. Clin Liver Dis. 2018 08; 22(3):501-515.
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Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies. PLoS Pathog. 2018 03; 14(3):e1006935.
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The homozygous CX3CR1-M280 mutation impairs human monocyte survival. JCI Insight. 2018 02 08; 3(3).
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CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis. PLoS One. 2017; 12(8):e0182643.