"Serine Proteases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide hydrolases that contain at the active site a SERINE residue involved in catalysis.
| Descriptor ID |
D057057
|
| MeSH Number(s) |
D08.811.277.656.959
|
| Concept/Terms |
Serine Proteases- Serine Proteases
- Proteases, Serine
- Serine Proteinases
- Proteinases, Serine
- Serine Proteinase
- Proteinase, Serine
- Serine Protease
- Protease, Serine
- Serine Protein Hydrolases
- Protein Hydrolases, Serine
|
Below are MeSH descriptors whose meaning is more general than "Serine Proteases".
Below are MeSH descriptors whose meaning is more specific than "Serine Proteases".
This graph shows the total number of publications written about "Serine Proteases" by people in this website by year, and whether "Serine Proteases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 2 | 4 | 6 |
| 2018 | 2 | 1 | 3 |
| 2020 | 0 | 3 | 3 |
| 2021 | 1 | 2 | 3 |
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Below are the most recent publications written about "Serine Proteases" by people in Profiles.
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Interfering with Host Proteases in SARS-CoV-2 Entry as a Promising Therapeutic Strategy. Curr Med Chem. 2022; 29(4):635-665.
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Covid-19: Pathophysiology; Mechanism of Transmission and Possible Molecular Drug Target for Management. Curr Mol Pharmacol. 2021 10 25; 14(4):509-519.
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The ß-link motif in protein architecture. Acta Crystallogr D Struct Biol. 2021 Aug 01; 77(Pt 8):1040-1049.
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Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat. J Virol. 2021 09 09; 95(19):e0086121.
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Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation. Elife. 2021 04 09; 10.
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In-silico screening for identification of potential inhibitors against SARS-CoV-2 transmembrane serine protease 2 (TMPRSS2). Eur J Pharm Sci. 2021 Jul 01; 162:105820.
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Structural leitmotif and functional variations of the structural catalytic core in (chymo)trypsin-like serine/cysteine fold proteinases. Int J Biol Macromol. 2021 May 15; 179:601-609.
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Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine. 2021 Mar; 65:103255.
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TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein. Viruses. 2021 02 28; 13(3).
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Targeting SARS-CoV-2 M3CLpro by HCV NS3/4a Inhibitors: In Silico Modeling and In Vitro Screening. J Chem Inf Model. 2021 02 22; 61(2):1020-1032.