"Click Chemistry" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.
| Descriptor ID |
D057930
|
| MeSH Number(s) |
E05.197.124 J01.897.836.249.124
|
| Concept/Terms |
Click Chemistry- Click Chemistry
- Chemistries, Click
- Chemistry, Click
- Click Chemistries
- Click Chemical Techniques
- Chemical Technique, Click
- Chemical Techniques, Click
- Click Chemical Technique
- Technique, Click Chemical
- Techniques, Click Chemical
Click Chemical Reactions- Click Chemical Reactions
- Chemical Reaction, Click
- Chemical Reactions, Click
- Click Chemical Reaction
- Reaction, Click Chemical
- Reactions, Click Chemical
|
Below are MeSH descriptors whose meaning is more general than "Click Chemistry".
Below are MeSH descriptors whose meaning is more specific than "Click Chemistry".
This graph shows the total number of publications written about "Click Chemistry" by people in this website by year, and whether "Click Chemistry" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 2 | 2 |
| 2018 | 2 | 2 | 4 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Click Chemistry" by people in Profiles.
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ACE2 Receptor-Modified Algae-Based Microrobot for Removal of SARS-CoV-2 in Wastewater. J Am Chem Soc. 2021 08 11; 143(31):12194-12201.
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Synthesis and characterisation of N-gene targeted NIR-II fluorescent probe for selective localisation of SARS-CoV-2. Chem Commun (Camb). 2021 Jun 24; 57(51):6229-6232.
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New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2. Bioorg Chem. 2021 09; 114:105117.
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Essential requirement for JPT2 in NAADP-evoked Ca2+ signaling. Sci Signal. 2021 03 23; 14(675).
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Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs. Biomolecules. 2020 12 11; 10(12).
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Supersensitive Multifluorophore RNA-FISH for Early Virus Detection and Flow-FISH by Using Click Chemistry. Chembiochem. 2020 08 03; 21(15):2214-2218.
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Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells. Chem Commun (Camb). 2019 Sep 10; 55(73):10952-10955.
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Surface Immobilization of Viruses and Nanoparticles Elucidates Early Events in Clathrin-Mediated Endocytosis. ACS Infect Dis. 2018 11 09; 4(11):1585-1600.
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Sterically shielded tetrazoles for a fluorogenic photoclick reaction: tuning cycloaddition rate and product fluorescence. Org Biomol Chem. 2018 07 25; 16(29):5241-5244.
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Cell Lysate Microarray for Mapping the Network of Genetic Regulators for Histone Marks. Mol Cell Proteomics. 2018 09; 17(9):1720-1736.