"Sarcoma, Synovial" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)
| Descriptor ID |
D013584
|
| MeSH Number(s) |
C04.557.450.565.835 C04.557.450.795.875
|
| Concept/Terms |
Sarcoma, Synovial- Sarcoma, Synovial
- Sarcomas, Synovial
- Synovial Sarcoma
- Synovial Sarcomas
- Synovioma
- Synoviomas
|
Below are MeSH descriptors whose meaning is more general than "Sarcoma, Synovial".
Below are MeSH descriptors whose meaning is more specific than "Sarcoma, Synovial".
This graph shows the total number of publications written about "Sarcoma, Synovial" by people in this website by year, and whether "Sarcoma, Synovial" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 2 | 2 | 4 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sarcoma, Synovial" by people in Profiles.
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A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients. BMC Cancer. 2018 Jun 08; 18(1):646.
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First-in-Human Treatment With a Dendritic Cell-targeting Lentiviral Vector-expressing NY-ESO-1, LV305, Induces Deep, Durable Response in Refractory Metastatic Synovial Sarcoma Patient. J Immunother. 2017 10; 40(8):302-306.
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Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial. Lancet Oncol. 2017 06; 18(6):812-822.
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Synovial Sarcoma With Intracranial Metastasis as the Site of Reoccurrence. Am J Med Sci. 2017 Nov; 354(5):523-526.
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REGOSARC: Regorafenib versus placebo in doxorubicin-refractory soft-tissue sarcoma-A quality-adjusted time without symptoms of progression or toxicity analysis. Cancer. 2017 Jun 15; 123(12):2294-2302.
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Trabectedin in advanced synovial sarcomas: a multicenter retrospective study from four European institutions and the Italian Rare Cancer Network. Anticancer Drugs. 2015 Jul; 26(6):678-81.
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Sarcomas with spindle cell morphology. Semin Oncol. 2009 Aug; 36(4):324-37.
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Microvascular reconstruction of the mandible in irradiated patients. J Craniofac Surg. 2007 Nov; 18(6):1359-69.