"Lactams" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.
| Descriptor ID |
D007769
|
| MeSH Number(s) |
D02.065.589 D03.383.411
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lactams".
Below are MeSH descriptors whose meaning is more specific than "Lactams".
This graph shows the total number of publications written about "Lactams" by people in this website by year, and whether "Lactams" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lactams" by people in Profiles.
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Supervised Molecular Dynamics (SuMD) Insights into the mechanism of action of SARS-CoV-2 main protease inhibitor PF-07321332. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):1646-1650.
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Optimizing preoperative antibiotics in patients with ß-lactam allergies: A role for pharmacy. Am J Health Syst Pharm. 2021 Aug 30; 78(Supplement_3):S76-S82.
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Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors. Bioorg Med Chem Lett. 2021 10 15; 50:128333.
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Potential Repurposed Therapeutics and New Vaccines against COVID-19 and Their Clinical Status. SLAS Discov. 2020 12; 25(10):1097-1107.
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a-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment. J Med Chem. 2020 05 14; 63(9):4562-4578.
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New onset myasthenia gravis in a patient with non small cell lung cancer treated with lorlatinib a novel anti-cancer agent. J Neurol Sci. 2018 09 15; 392:100-101.
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Oncogene addiction in non-small cell lung cancer: Focus on ROS1 inhibition. Cancer Treat Rev. 2017 Apr; 55:83-95.
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PdII/AgI-Catalyzed Room-Temperature Reaction of ?-Hydroxy Lactams: Mechanism, Scope, and Antistaphylococcal Activity. J Org Chem. 2017 02 17; 82(4):2193-2198.
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The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect. Pharmacol Ther. 2016 06; 162:179-87.
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Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors. J Med Chem. 2005 Nov 03; 48(22):6767-71.