Plasminogen Activator Inhibitor 1
"Plasminogen Activator Inhibitor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
| Descriptor ID |
D017395
|
| MeSH Number(s) |
D12.644.861.695.500 D12.776.124.125.640 D12.776.872.695.500 D23.119.832.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Plasminogen Activator Inhibitor 1".
Below are MeSH descriptors whose meaning is more specific than "Plasminogen Activator Inhibitor 1".
This graph shows the total number of publications written about "Plasminogen Activator Inhibitor 1" by people in this website by year, and whether "Plasminogen Activator Inhibitor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 6 | 9 |
| 2018 | 5 | 6 | 11 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 2 | 2 |
| 2021 | 2 | 4 | 6 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Plasminogen Activator Inhibitor 1" by people in Profiles.
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Distinctive Biomarker Features in the Endotheliopathy of COVID-19 and Septic Syndromes. Shock. 2022 01 01; 57(1):95-105.
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ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial PAI-1. Am J Respir Cell Mol Biol. 2021 09; 65(3):300-308.
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The Central Role of PAI-1 in COVID-19: Thrombosis and beyond. Am J Respir Cell Mol Biol. 2021 09; 65(3):238-240.
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Biomarkers of endothelial dysfunction and outcomes in coronavirus disease 2019 (COVID-19) patients: A systematic review and meta-analysis. Microvasc Res. 2021 11; 138:104224.
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Dysregulation of Pulmonary Responses in Severe COVID-19. Viruses. 2021 05 21; 13(6).
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Endothelial cell dysfunction, coagulation, and angiogenesis in coronavirus disease 2019 (COVID-19). Microvasc Res. 2021 09; 137:104188.
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Biomarkers of coagulation, endothelial function, and fibrinolysis in critically ill patients with COVID-19: A single-center prospective longitudinal study. J Thromb Haemost. 2021 06; 19(6):1546-1557.
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Dissemination of extreme levels of extracellular vesicles: tissue factor activity in patients with severe COVID-19. Blood Adv. 2021 02 09; 5(3):628-634.
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Sustained prothrombotic changes in COVID-19 patients 4 months after hospital discharge. Blood Adv. 2021 02 09; 5(3):756-759.
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Circulating Levels of Tissue Plasminogen Activator and Plasminogen Activator Inhibitor-1 Are Independent Predictors of Coronavirus Disease 2019 Severity: A Prospective, Observational Study. Semin Thromb Hemost. 2021 06; 47(4):451-455.