Sodium-Hydrogen Exchangers
"Sodium-Hydrogen Exchangers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of plasma membrane exchange glycoprotein antiporters that transport sodium ions and protons across lipid bilayers. They have critical functions in intracellular pH regulation, cell volume regulation, and cellular response to many different hormones and mitogens.
Descriptor ID |
D017923
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MeSH Number(s) |
D12.776.157.530.450.162.775 D12.776.157.530.937.703 D12.776.543.550.190.775 D12.776.543.585.450.162.775 D12.776.543.585.937.828
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Concept/Terms |
Sodium-Hydrogen Exchangers- Sodium-Hydrogen Exchangers
- Exchangers, Sodium-Hydrogen
- Sodium Hydrogen Exchangers
- Na(+)-H(+)-Antiporter
- Na(+)-H(+)-Exchangers
- Sodium-Proton Antiporters
- Antiporters, Sodium-Proton
- Sodium Proton Antiporters
- Solute Carrier 9 Proteins
- SLC9 Na(+)-H(+) Exchangers
- SLC9 Protein Family
- Protein Family, SLC9
- SLC9-NHE Protein Family
- Protein Family, SLC9-NHE
- SLC9 NHE Protein Family
- SLC9 Proteins
- Solute Carrier 9 Protein Family
- Sodium-Hydrogen Antiporter
- Antiporter, Sodium-Hydrogen
- Sodium Hydrogen Antiporter
- Na(+)-H(+)-Exchanger
- Sodium-Hydrogen Exchanger
- Exchanger, Sodium-Hydrogen
- Sodium Hydrogen Exchanger
- Sodium-Proton Antiporter
- Antiporter, Sodium-Proton
- Sodium Proton Antiporter
- Sodium-Hydrogen Antiporters
- Antiporters, Sodium-Hydrogen
- Sodium Hydrogen Antiporters
- Na(+)-H(+)-Antiporters
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Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchangers".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchangers".
This graph shows the total number of publications written about "Sodium-Hydrogen Exchangers" by people in this website by year, and whether "Sodium-Hydrogen Exchangers" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2013 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2017 | 4 | 1 | 5 |
2018 | 3 | 0 | 3 |
2020 | 1 | 1 | 2 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Hydrogen Exchangers" by people in Profiles.
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Effects of the Na+/H+ Ion Exchanger on Susceptibility to COVID-19 and the Course of the Disease. J Renin Angiotensin Aldosterone Syst. 2021; 2021:4754440.
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Might proton pump or sodium-hydrogen exchanger inhibitors be of value to ameliorate SARs-CoV-2 pathophysiology? Physiol Rep. 2021 01; 8(24):e14649.
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SGLT2 inhibition and COVID-19: The road not taken. Eur J Clin Invest. 2020 Dec; 50(12):e13339.
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COVID-19 may affect the endocrine pancreas by activating Na+/H+ exchanger 2 and increasing lactate levels. J Endocrinol Invest. 2020 Aug; 43(8):1167-1168.
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Cyclosporine therapy in cytokine storm due to coronavirus disease 2019 (COVID-19). Rheumatol Int. 2020 07; 40(7):1177-1179.
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Diverse residues of intracellular loop 5 of the Na+/H+ exchanger modulate proton sensing, expression, activity and targeting. Biochim Biophys Acta Biomembr. 2019 01; 1861(1):191-200.
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Inhibition of the Sodium-Proton Antiporter (Exchanger) is a Plausible Mechanism of Potential Benefit and Harm for Drugs Designed to Block Sodium Glucose Co-transporter 2. Rev Cardiovasc Med. 2018 Jun 30; 19(2):51-63.
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NHERF1 and tumor microenvironment: a new scene in invasive breast carcinoma. J Exp Clin Cancer Res. 2018 May 02; 37(1):96.
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The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Rep. 2017 11; 18(11):2015-2029.
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Effects of Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Patients With Heart Failure: Proposal of a Novel Mechanism of Action. JAMA Cardiol. 2017 09 01; 2(9):1025-1029.