"Thrombomodulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell surface glycoprotein of endothelial cells that binds thrombin and serves as a cofactor in the activation of protein C and its regulation of blood coagulation.
| Descriptor ID |
D018180
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| MeSH Number(s) |
D12.776.395.550.625.800.800 D12.776.543.550.625.800.800 D12.776.543.750.705.675.892.800 D12.776.543.750.750.850.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thrombomodulin".
Below are MeSH descriptors whose meaning is more specific than "Thrombomodulin".
This graph shows the total number of publications written about "Thrombomodulin" by people in this website by year, and whether "Thrombomodulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2017 | 5 | 5 | 10 |
| 2018 | 2 | 3 | 5 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thrombomodulin" by people in Profiles.
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Distinctive Biomarker Features in the Endotheliopathy of COVID-19 and Septic Syndromes. Shock. 2022 01 01; 57(1):95-105.
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Biomarkers of endothelial dysfunction and outcomes in coronavirus disease 2019 (COVID-19) patients: A systematic review and meta-analysis. Microvasc Res. 2021 11; 138:104224.
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Genetic justification of severe COVID-19 using a rigorous algorithm. Clin Immunol. 2021 05; 226:108726.
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SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung. Elife. 2021 03 08; 10.
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Thrombin generation in patients with COVID-19 with and without thromboprophylaxis. Clin Chem Lab Med. 2021 06 25; 59(7):1323-1330.
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Thrombin Generation in Patients with Coronavirus Disease 2019. Semin Thromb Hemost. 2021 06; 47(4):447-450.
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Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19? Anesth Analg. 2020 09; 131(3):690-693.
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The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial. Trials. 2020 Aug 26; 21(1):746.
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Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial. JAMA. 2019 10 01; 322(13):1261-1270.
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Recombinant human soluble thrombomodulin in patients with sepsis-associated coagulopathy (SCARLET): an updated meta-analysis. Crit Care. 2019 09 05; 23(1):302.