"Etoposide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
| Descriptor ID |
D005047
|
| MeSH Number(s) |
D02.455.426.559.847.638.960.675.250 D04.615.638.960.675.250 D09.408.348.275
|
| Concept/Terms |
Etoposide- Etoposide
- Demethyl Epipodophyllotoxin Ethylidine Glucoside
- Eposide
Toposar- Toposar
- Etoposide Teva
- Teva, Etoposide
|
Below are MeSH descriptors whose meaning is more general than "Etoposide".
Below are MeSH descriptors whose meaning is more specific than "Etoposide".
This graph shows the total number of publications written about "Etoposide" by people in this website by year, and whether "Etoposide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 2 | 15 | 17 |
| 2018 | 1 | 6 | 7 |
| 2019 | 1 | 2 | 3 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Etoposide" by people in Profiles.
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Cyclophosphamide plus etoposide is a safe and effective mobilization regimen in patients with multiple myeloma. Transfus Apher Sci. 2021 Oct; 60(5):103197.
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Etoposide for Cytokine Storm Because of Coronavirus Disease 2019. Chest. 2021 04; 159(4):1678-1679.
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Four Cycles of Etoposide plus Cisplatin for Patients with Good-Risk Advanced Germ Cell Tumors. Oncologist. 2021 06; 26(6):483-491.
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Familial hemophagocytic lymphohistiocytosis induced by SARS-CoV-2. Pediatr Hematol Oncol. 2021 05; 38(4):406-409.
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COVID-19 reinfection in two children with cancer. Pediatr Hematol Oncol. 2021 05; 38(4):403-405.
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Etoposide as Salvage Therapy for Cytokine Storm Due to Coronavirus Disease 2019. Chest. 2021 01; 159(1):e7-e11.
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The AI-discovered aetiology of COVID-19 and rationale of the irinotecan+ etoposide combination therapy for critically ill COVID-19 patients. Med Hypotheses. 2020 Nov; 144:110180.
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Etoposide treatment adjunctive to immunosuppressants for critically ill COVID-19 patients. J Infect. 2020 09; 81(3):452-482.
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Potential Treatments for COVID-19 Related Cytokine Storm - Beyond Corticosteroids. Front Immunol. 2020; 11:1445.
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Secondary hemophagocytic lymphohistiocytosis, HScore and COVID-19. Int J Hematol. 2020 Jul; 112(1):125-126.