"Axin Signaling Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.
| Descriptor ID |
D060465
|
| MeSH Number(s) |
D05.500.117 D12.776.476.081
|
| Concept/Terms |
Axin Signaling Complex- Axin Signaling Complex
- Signaling Complex, Axin
- Axin Signaling Complex Proteins
- beta-Catenin Destruction Complex
- Destruction Complex, beta-Catenin
- beta Catenin Destruction Complex
|
Below are MeSH descriptors whose meaning is more general than "Axin Signaling Complex".
Below are MeSH descriptors whose meaning is more specific than "Axin Signaling Complex".
This graph shows the total number of publications written about "Axin Signaling Complex" by people in this website by year, and whether "Axin Signaling Complex" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Axin Signaling Complex" by people in Profiles.
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Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ. Oncogene. 2017 08 10; 36(32):4573-4584.