CRISPR-Associated Proteins
"CRISPR-Associated Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.
| Descriptor ID |
D064130
|
| MeSH Number(s) |
D12.776.212
|
| Concept/Terms |
CRISPR-Associated Protein Complex Proteins- CRISPR-Associated Protein Complex Proteins
- CRISPR Associated Protein Complex Proteins
- CRISPR-Associated Complex for Antiviral Defense Proteins
- CRISPR Associated Complex for Antiviral Defense Proteins
- CASCADE Proteins, CRISPR-Associated
- CASCADE Proteins, CRISPR Associated
- CRISPR-Associated CASCADE Proteins
|
Below are MeSH descriptors whose meaning is more general than "CRISPR-Associated Proteins".
Below are MeSH descriptors whose meaning is more specific than "CRISPR-Associated Proteins".
This graph shows the total number of publications written about "CRISPR-Associated Proteins" by people in this website by year, and whether "CRISPR-Associated Proteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2017 | 3 | 3 | 6 |
| 2018 | 3 | 0 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 3 | 1 | 4 |
| 2021 | 1 | 4 | 5 |
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Below are the most recent publications written about "CRISPR-Associated Proteins" by people in Profiles.
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SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. Nat Commun. 2021 08 19; 12(1):5033.
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Recent progress on rapid SARS-CoV-2/COVID-19 detection by CRISPR-Cas13-based platforms. Drug Discov Today. 2021 08; 26(8):2025-2035.
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An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing. Nat Commun. 2021 03 19; 12(1):1739.
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Detection of SARS-CoV-2 by CRISPR/Cas12a-Enhanced Colorimetry. ACS Sens. 2021 03 26; 6(3):1086-1093.
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Rapid, Ultrasensitive, and Highly Specific Diagnosis of COVID-19 by CRISPR-Based Detection. ACS Sens. 2021 03 26; 6(3):881-888.
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Development of a Broadly Applicable Cas12a-Linked Beam Unlocking Reaction for Sensitive and Specific Detection of Respiratory Pathogens Including SARS-CoV-2. ACS Chem Biol. 2021 03 19; 16(3):491-500.
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Reverse Transcription Recombinase Polymerase Amplification Coupled with CRISPR-Cas12a for Facile and Highly Sensitive Colorimetric SARS-CoV-2 Detection. Anal Chem. 2021 03 02; 93(8):4126-4133.
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Commentary - CRISPR-based techniques: Cas9, Cas13 and their applications in the era of COVID-19. Eur Rev Med Pharmacol Sci. 2021 Feb; 25(3):1752-1761.
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Comparative performance of CRISPR-Cas12a assays for SARS-CoV-2 detection tested with RNA extracted from clinical specimens. J Virol Methods. 2021 04; 290:114092.
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Detection of SARS-CoV-2 and Its Mutated Variants via CRISPR-Cas13-Based Transcription Amplification. Anal Chem. 2021 02 23; 93(7):3393-3402.