"Cytochrome P-450 CYP2B6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE.
| Descriptor ID |
D065702
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| MeSH Number(s) |
D08.244.453.005.575 D08.244.453.491.344 D08.811.682.690.708.170.010.575 D08.811.682.690.708.170.450.344 D12.776.422.220.453.010.575 D12.776.422.220.453.491.344
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| Concept/Terms |
Cytochrome P-450 CYP2B6- Cytochrome P-450 CYP2B6
- CYP2B6, Cytochrome P-450
- Cytochrome P 450 CYP2B6
- P-450 CYP2B6, Cytochrome
- CYPIIB6
- 1,4-Cineole 2-exo-Monooxygenase
- 1,4 Cineole 2 exo Monooxygenase
- 2-exo-Monooxygenase, 1,4-Cineole
- Cytochrome P450 2B6
- P450 2B6, Cytochrome
- CYP2B6
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP2B6".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP2B6".
This graph shows the total number of publications written about "Cytochrome P-450 CYP2B6" by people in this website by year, and whether "Cytochrome P-450 CYP2B6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 3 | 0 | 3 |
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Below are the most recent publications written about "Cytochrome P-450 CYP2B6" by people in Profiles.
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Occurrence of CYP2B6 516G>T polymorphism in patients with ARV-associated hepatotoxicity. Mol Genet Genomic Med. 2019 04; 7(4):e00598.
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Cytochrome P450 CYP2B6*6 distribution among Congolese individuals with HIV, Tuberculosis and Malaria infection. Int J Infect Dis. 2019 May; 82:111-116.
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Halogen Substitution Influences Ketamine Metabolism by Cytochrome P450 2B6: In Vitro and Computational Approaches. Mol Pharm. 2019 02 04; 16(2):898-906.
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CYP2B6 Genetic Polymorphisms, Depression, and Viral Suppression in Adults Living with HIV Initiating Efavirenz-Containing Antiretroviral Therapy Regimens in Uganda: Pooled Analysis of Two Prospective Studies. AIDS Res Hum Retroviruses. 2018 11; 34(11):982-992.
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Prediction of plasma efavirenz concentrations among HIV-positive patients taking efavirenz-containing combination antiretroviral therapy. Sci Rep. 2017 11 23; 7(1):16187.
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Effect of CYP2B6 Gene Polymorphisms on Efavirenz Plasma Concentrations in Chinese Patients with HIV Infection. PLoS One. 2015; 10(6):e0130583.