"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
|
| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
|
| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 2 | 0 | 2 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 3 | 4 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 6 | 6 |
| 2005 | 1 | 8 | 9 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 5 | 5 |
| 2008 | 0 | 3 | 3 |
| 2009 | 3 | 4 | 7 |
| 2010 | 1 | 4 | 5 |
| 2011 | 3 | 5 | 8 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 6 | 6 |
| 2014 | 2 | 2 | 4 |
| 2015 | 1 | 3 | 4 |
| 2016 | 3 | 11 | 14 |
| 2017 | 30 | 95 | 125 |
| 2018 | 30 | 81 | 111 |
| 2019 | 8 | 38 | 46 |
| 2020 | 9 | 33 | 42 |
| 2021 | 11 | 27 | 38 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Defining Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placentitis. Arch Pathol Lab Med. 2021 11 01; 145(11):1341-1349.
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Attenuated activation of pulmonary immune cells in mRNA-1273-vaccinated hamsters after SARS-CoV-2 infection. J Clin Invest. 2021 10 15; 131(20).
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Maturation signatures of conventional dendritic cell subtypes in COVID-19 suggest direct viral sensing. Eur J Immunol. 2022 01; 52(1):109-122.
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CD8+PD-L1+CXCR3+ polyfunctional T cell abundances are associated with survival in critical SARS-CoV-2-infected patients. JCI Insight. 2021 09 22; 6(18).
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SARS-CoV-2-reactive T-cell receptors isolated from convalescent COVID-19 patients confer potent T-cell effector function. Eur J Immunol. 2021 11; 51(11):2651-2664.
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Specific detection of memory T-cells in COVID-19 patients using standardized whole-blood Interferon gammarelease assay. Eur J Immunol. 2021 12; 51(12):3239-3242.
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Suppressive Monocytes Impair MAIT Cells Response via IL-10 in Patients with Severe COVID-19. J Immunol. 2021 10 01; 207(7):1848-1856.
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Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells. Mucosal Immunol. 2021 11; 14(6):1381-1392.
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Brief report: Tempol, a novel antioxidant, inhibits both activated T cell and antigen presenting cell derived cytokines in-vitro from COVID-19 patients. Clin Immunol. 2021 10; 231:108828.
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Activation or exhaustion of CD8+ T cells in patients with COVID-19. Cell Mol Immunol. 2021 10; 18(10):2325-2333.