"Microsomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
| Descriptor ID |
D008861
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| MeSH Number(s) |
A11.284.835.540
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microsomes".
Below are MeSH descriptors whose meaning is more specific than "Microsomes".
This graph shows the total number of publications written about "Microsomes" by people in this website by year, and whether "Microsomes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microsomes" by people in Profiles.
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Design, synthesis and biological evaluation of 2-aminoquinazolin-4(3H)-one derivatives as potential SARS-CoV-2 and MERS-CoV treatments. Bioorg Med Chem Lett. 2021 05 01; 39:127885.
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Remdesivir potently inhibits carboxylesterase-2 through covalent modifications: signifying strong drug-drug interactions. Fundam Clin Pharmacol. 2021 Apr; 35(2):432-434.
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SARS-CoV-2 envelope protein topology in eukaryotic membranes. Open Biol. 2020 09; 10(9):200209.
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Cyclooxygenase and prostaglandin synthases: roles in plaque stability and instability in humans. Curr Opin Lipidol. 2009 Oct; 20(5):402-8.
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Transport of the intracisternal A-type particle Gag polyprotein to the endoplasmic reticulum is mediated by the signal recognition particle. J Virol. 2003 Jun; 77(11):6293-304.
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Membrane topology of coronavirus E protein. Virology. 2001 Mar 15; 281(2):163-9.
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Processing of the coronavirus MHV-JHM polymerase polyprotein: identification of precursors and proteolytic products spanning 400 kilodaltons of ORF1a. Virology. 1998 Mar 15; 242(2):288-302.
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Localization of antigenic sites of the S glycoprotein of feline infectious peritonitis virus involved in neutralization and antibody-dependent enhancement. J Virol. 1995 May; 69(5):2858-62.
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A novel glycoprotein of feline infectious peritonitis coronavirus contains a KDEL-like endoplasmic reticulum retention signal. Adv Exp Med Biol. 1993; 342:209-14.
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Membrane integration and intracellular transport of the coronavirus glycoprotein E1, a class III membrane glycoprotein. J Biol Chem. 1988 Oct 15; 263(29):14956-63.