"5'-Nucleotidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5.
| Descriptor ID |
D015720
|
| MeSH Number(s) |
D08.811.277.352.650.600.600
|
| Concept/Terms |
5'-Nucleotidase- 5'-Nucleotidase
- 5' Nucleotidase
- 5'-Nucleotidase Phosphoribolase
- 5' Nucleotidase Phosphoribolase
- Adenylate Phosphatase
- AMP Phosphatase
- Cytidylate Phosphatase
- Ecto-5'-Nucleotidase
- Ecto 5' Nucleotidase
- IMP Nucleotidase
- CD73 Antigens
- IMPase
- Inosinate Phosphatase
- Pyrimidine 5'-Nucleotidase
- Pyrimidine 5' Nucleotidase
- Thymidine Phosphatase
- Uridylate 5'-Nucleotidase
- Uridylate 5' Nucleotidase
- Antigen, CD73
- CD73 Antigen
- Antigens, CD73
- 5'-AMP Nucleotidase
- 5' AMP Nucleotidase
- IMP Phosphatase
|
Below are MeSH descriptors whose meaning is more general than "5'-Nucleotidase".
Below are MeSH descriptors whose meaning is more specific than "5'-Nucleotidase".
This graph shows the total number of publications written about "5'-Nucleotidase" by people in this website by year, and whether "5'-Nucleotidase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 3 | 1 | 4 |
| 2018 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "5'-Nucleotidase" by people in Profiles.
-
Defining the CD39/CD73 Axis in SARS-CoV-2 Infection: The CD73- Phenotype Identifies Polyfunctional Cytotoxic Lymphocytes. Cells. 2020 07 22; 9(8).
-
A novel secreted-cAMP pathway inhibits pulmonary hypertension via a feed-forward mechanism. Cardiovasc Res. 2020 07 01; 116(8):1500-1513.
-
Targeting adenosinergic pathway and adenosine A2A receptor signaling for the treatment of COVID-19: A hypothesis. Med Hypotheses. 2020 Nov; 144:110012.
-
Methotrexate and BAFF interaction prevents immunization against TNF inhibitors. Ann Rheum Dis. 2018 10; 77(10):1463-1470.
-
CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells. Stem Cell Reports. 2018 04 10; 10(4):1412-1425.
-
Soluble CD73 as biomarker in patients with metastatic melanoma patients treated with nivolumab. J Transl Med. 2017 12 04; 15(1):244.
-
Cellular Prion Protein PrPC and Ecto-5'-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy. Cancer Res. 2017 06 01; 77(11):2914-2926.
-
Down-regulation of CD73 on B cells of patients with viremic HIV correlates with B cell activation and disease progression. J Leukoc Biol. 2017 05; 101(5):1263-1271.
-
Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent. Nat Commun. 2017 02 07; 8:14108.
-
Effect of inapparent murine hepatitis virus infections on macrophages and host resistance. J Leukoc Biol. 1986 May; 39(5):559-65.