"Pyrrolizidine Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
| Descriptor ID |
D011763
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| MeSH Number(s) |
D03.132.716 D03.633.100.772
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrrolizidine Alkaloids".
Below are MeSH descriptors whose meaning is more specific than "Pyrrolizidine Alkaloids".
This graph shows the total number of publications written about "Pyrrolizidine Alkaloids" by people in this website by year, and whether "Pyrrolizidine Alkaloids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyrrolizidine Alkaloids" by people in Profiles.
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Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models. Mol Med Rep. 2018 Jun; 17(6):7757-7763.