"4-Butyrolactone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
| Descriptor ID |
D015107
|
| MeSH Number(s) |
D02.540.150 D03.383.312.150
|
| Concept/Terms |
4-Butyrolactone- 4-Butyrolactone
- 4 Butyrolactone
- Dihydro-2(3H)-furanone
- gamma-Butyrolactone
- gamma Butyrolactone
- Furanone, tetrahydro-2-
- Furanone, tetrahydro 2
- 1,4-Butanolide
- 1,4 Butanolide
- 4-Hydroxybutyric Acid Lactone
- 4 Hydroxybutyric Acid Lactone
- Lactone, 4-Hydroxybutyric Acid
|
Below are MeSH descriptors whose meaning is more general than "4-Butyrolactone".
Below are MeSH descriptors whose meaning is more specific than "4-Butyrolactone".
This graph shows the total number of publications written about "4-Butyrolactone" by people in this website by year, and whether "4-Butyrolactone" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "4-Butyrolactone" by people in Profiles.
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Anti-Inflammatory, Antiallergic, and COVID-19 Main Protease (Mpro) Inhibitory Activities of Butenolides from a Marine-Derived Fungus Aspergillus terreus. Molecules. 2021 Jun 02; 26(11).
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Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study. Lancet Oncol. 2018 04; 19(4):521-536.
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Identification, synthesis and regulatory function of the N-acylated homoserine lactone signals produced by Pseudomonas chlororaphis HT66. Microb Cell Fact. 2018 Jan 22; 17(1):9.
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Cembrene Diterpenoids with Ether Linkages from Sarcophyton ehrenbergi: An Anti-Proliferation and Molecular-Docking Assessment. Mar Drugs. 2017 Jun 21; 15(6).
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Coronin 1A, a novel player in integrin biology, controls neutrophil trafficking in innate immunity. Blood. 2017 08 17; 130(7):847-858.
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Intoxication by gamma hydroxybutyrate and related analogues: Clinical characteristics and comparison between pure intoxication and that combined with other substances of abuse. Toxicol Lett. 2017 Aug 05; 277:84-91.
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Management and treatment of gamma butyrolactone withdrawal syndrome: a case report and review. J Psychiatr Pract. 2014 Jul; 20(4):294-300.