"Pyrophosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of enzymes within the class EC 3.6.1.- that catalyze the hydrolysis of diphosphate bonds, chiefly in nucleoside di- and triphosphates. They may liberate either a mono- or diphosphate. EC 3.6.1.-.
| Descriptor ID |
D011755
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| MeSH Number(s) |
D08.811.277.040.600
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrophosphatases".
Below are MeSH descriptors whose meaning is more specific than "Pyrophosphatases".
This graph shows the total number of publications written about "Pyrophosphatases" by people in this website by year, and whether "Pyrophosphatases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 4 | 2 | 6 |
| 2018 | 5 | 1 | 6 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pyrophosphatases" by people in Profiles.
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ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4. Proc Natl Acad Sci U S A. 2021 01 12; 118(2).
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Microbial Musings - December 2020. Microbiology (Reading). 2020 12; 166(12):1107-1109.
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A novel secreted-cAMP pathway inhibits pulmonary hypertension via a feed-forward mechanism. Cardiovasc Res. 2020 07 01; 116(8):1500-1513.
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Sequence homology between human PARP14 and the SARS-CoV-2 ADP ribose 1'-phosphatase. Immunol Lett. 2020 08; 224:38-39.
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Small alarmones (p)ppGpp regulate virulence associated traits and pathogenesis of Salmonella enterica serovar Typhi. Cell Microbiol. 2019 08; 21(8):e13034.
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The ADP-ribose reactive NUDIX hydrolase isoforms can modulate HIF-1a in cancer cells. Biochem Biophys Res Commun. 2018 09 26; 504(1):321-327.
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Coronary pathology of inherited generalized arterial calcification of infancy: a case report. Cardiovasc Pathol. 2018 Sep - Oct; 36:15-19.
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Basophil biomarkers as useful predictors for sublingual immunotherapy in allergic rhinitis. Int Immunopharmacol. 2018 Jul; 60:50-58.
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The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release. J Biol Chem. 2018 05 25; 293(21):7969-7981.
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The hepatic ectonucleotide pyrophosphatase/phosphodiesterase 1 gene mRNA abundance is reduced by insulin and induced by dexamethasone. Braz J Med Biol Res. 2018 Mar 01; 51(4):e6980.