"Quinine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
| Descriptor ID |
D011803
|
| MeSH Number(s) |
D03.132.206.719 D03.605.687.762 D03.633.100.810.762
|
| Concept/Terms |
Quinine Sulfate- Quinine Sulfate
- Sulfate, Quinine
- Quinine Sulphate
- Sulphate, Quinine
|
Below are MeSH descriptors whose meaning is more general than "Quinine".
Below are MeSH descriptors whose meaning is more specific than "Quinine".
This graph shows the total number of publications written about "Quinine" by people in this website by year, and whether "Quinine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 0 | 5 | 5 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Quinine" by people in Profiles.
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Predictive Significance of the Prognostic Nutritional Index (PNI) in Patients with Severe COVID-19. J Immunol Res. 2021; 2021:9917302.
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Quinine Inhibits Infection of Human Cell Lines with SARS-CoV-2. Viruses. 2021 04 09; 13(4).
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COVID-19 mimics endemic tropical diseases at an early stage: a report of two symptomatic COVID-19 patients treated in a polymerase chain reaction void zone in Cameroon. Pan Afr Med J. 2020; 37:212.
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Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup. J Am Soc Nephrol. 2020 10; 31(10):2475-2489.
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Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation. Bioorg Med Chem Lett. 2019 09 15; 29(18):2565-2570.
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Detection thresholds for quinine, PTC, and PROP measured using taste strips. Eur Arch Otorhinolaryngol. 2019 Mar; 276(3):753-759.
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High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure. BMC Med. 2018 10 01; 16(1):181.
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The Role of Quinine-Responsive Taste Receptor Family 2 in Airway Immune Defense and Chronic Rhinosinusitis. Front Immunol. 2018; 9:624.
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Case Report: Reversible Cerebral Vasoconstriction Syndrome in Cerebral Malaria. Am J Trop Med Hyg. 2018 02; 98(2):505-507.
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Validation of the identification of Streptococcus pneumoniae and oral streptococci by MALDI-TOF Microflex-LT. Ann Biol Clin (Paris). 2017 06 01; 75(3):356-358.